tetano
Editor, Senior Moderator
MMWR Morb Mortal Wkly Rep
. 2024 Sep 19;73(37):804-809.
doi: 10.15585/mmwr.mm7337a1.
Wastewater Surveillance for Influenza A Virus and H5 Subtype Concurrent with the Highly Pathogenic Avian Influenza A(H5N1) Virus Outbreak in Cattle and Poultry and Associated Human Cases - United States, May 12-July 13, 2024
Souci Louis, Miguella Mark-Carew, Matthew Biggerstaff, Jonathan Yoder, Alexandria B Boehm, Marlene K Wolfe, Matthew Flood, Susan Peters, Mary Grace Stobierski, Joseph Coyle, Matthew T Leslie, Mallory Sinner, Dawn Nims, Victoria Salinas, Layla Lustri, Heidi Bojes, Varun Shetty, Elisabeth Burnor, Angela Rabe, Guinevere Ellison-Giles, Alexander T Yu, Austin Bell, Stephanie Meyer, Ruth Lynfield, Melissa Sutton, Ryan Scholz, Rebecca Falender, Shannon Matzinger, Allison Wheeler, Farah S Ahmed, John Anderson, Kate Harris, Austin Walkins, Surabhi Bohra, Victoria O'Dell, Virginia T Guidry, Ariel Christensen, Zack Moore, Erica Wilson, Joshua L Clayton, Hannah Parsons, Krista Kniss, Alicia Budd, Jeffrey W Mercante, Heather E Reese, Michael Welton, Megan Bias, Jenna Webb, Daniel Cornforth, Scott Santibañez, Rieza H Soelaeman, Manpreet Kaur, Amy E Kirby, John R Barnes, Nicole Fehrenbach, Sonja J Olsen, Margaret A Honein
As part of the response to the highly pathogenic avian influenza A(H5N1) virus outbreak in U.S. cattle and poultry and the associated human cases, CDC and partners are monitoring influenza A virus levels and detection of the H5 subtype in wastewater. Among 48 states and the District of Columbia that performed influenza A testing of wastewater during May 12-July 13, 2024, a weekly average of 309 sites in 38 states had sufficient data for analysis, and 11 sites in four states reported high levels of influenza A virus. H5 subtype testing was conducted at 203 sites in 41 states, with H5 detections at 24 sites in nine states. For each detection or high level, CDC and state and local health departments evaluated data from other influenza surveillance systems and partnered with wastewater utilities and agriculture departments to investigate potential sources. Among the four states with high influenza A virus levels detected in wastewater, three states had corresponding evidence of human influenza activity from other influenza surveillance systems. Among the 24 sites with H5 detections, 15 identified animal sources within the sewershed or adjacent county, including eight milk-processing inputs. Data from these early investigations can help health officials optimize the use of wastewater surveillance during the upcoming respiratory illness season.
. 2024 Sep 19;73(37):804-809.
doi: 10.15585/mmwr.mm7337a1.
Wastewater Surveillance for Influenza A Virus and H5 Subtype Concurrent with the Highly Pathogenic Avian Influenza A(H5N1) Virus Outbreak in Cattle and Poultry and Associated Human Cases - United States, May 12-July 13, 2024
Souci Louis, Miguella Mark-Carew, Matthew Biggerstaff, Jonathan Yoder, Alexandria B Boehm, Marlene K Wolfe, Matthew Flood, Susan Peters, Mary Grace Stobierski, Joseph Coyle, Matthew T Leslie, Mallory Sinner, Dawn Nims, Victoria Salinas, Layla Lustri, Heidi Bojes, Varun Shetty, Elisabeth Burnor, Angela Rabe, Guinevere Ellison-Giles, Alexander T Yu, Austin Bell, Stephanie Meyer, Ruth Lynfield, Melissa Sutton, Ryan Scholz, Rebecca Falender, Shannon Matzinger, Allison Wheeler, Farah S Ahmed, John Anderson, Kate Harris, Austin Walkins, Surabhi Bohra, Victoria O'Dell, Virginia T Guidry, Ariel Christensen, Zack Moore, Erica Wilson, Joshua L Clayton, Hannah Parsons, Krista Kniss, Alicia Budd, Jeffrey W Mercante, Heather E Reese, Michael Welton, Megan Bias, Jenna Webb, Daniel Cornforth, Scott Santibañez, Rieza H Soelaeman, Manpreet Kaur, Amy E Kirby, John R Barnes, Nicole Fehrenbach, Sonja J Olsen, Margaret A Honein
- PMID: 39298357
- DOI: 10.15585/mmwr.mm7337a1
As part of the response to the highly pathogenic avian influenza A(H5N1) virus outbreak in U.S. cattle and poultry and the associated human cases, CDC and partners are monitoring influenza A virus levels and detection of the H5 subtype in wastewater. Among 48 states and the District of Columbia that performed influenza A testing of wastewater during May 12-July 13, 2024, a weekly average of 309 sites in 38 states had sufficient data for analysis, and 11 sites in four states reported high levels of influenza A virus. H5 subtype testing was conducted at 203 sites in 41 states, with H5 detections at 24 sites in nine states. For each detection or high level, CDC and state and local health departments evaluated data from other influenza surveillance systems and partnered with wastewater utilities and agriculture departments to investigate potential sources. Among the four states with high influenza A virus levels detected in wastewater, three states had corresponding evidence of human influenza activity from other influenza surveillance systems. Among the 24 sites with H5 detections, 15 identified animal sources within the sewershed or adjacent county, including eight milk-processing inputs. Data from these early investigations can help health officials optimize the use of wastewater surveillance during the upcoming respiratory illness season.