tetano
Editor, Senior Moderator
J Gen Virol. 2017 Nov 23. doi: 10.1099/jgv.0.000983. [Epub ahead of print]
[h=1]Molecular and phylogenetic analyses of influenza B viruses isolated from pediatric inpatients in South Korea during the 2011-2012 winter season.[/h] Nam JH[SUP]1[/SUP], Song EJ[SUP]1[/SUP], Song D[SUP]1[/SUP], Espa?o E[SUP]1[/SUP], Shim SM[SUP]2,[/SUP][SUP]1[/SUP], Jeong SH[SUP]1[/SUP], Webster RG[SUP]3[/SUP], Kim WJ[SUP]4[/SUP], Kim JK[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza B virus remains a major cause of respiratory diseases worldwide. Because of limited epidemiological and genetic data, the local and global transmission patterns of influenza B virus are not fully understood. Here we report the molecular and phylogenetic characterization of 163 influenza B virus isolates from pediatric inpatients with influenza-like illness in the winter of 2011-2012 in South Korea. Analysis of haemagglutinin and neuraminidase genes of the influenza B isolates revealed that both B/Victoria (62 %) and B/Yamagata lineages (38 %) co-circulated during that influenza season, and a considerable number of the isolates carried several amino acid substitutions in the four major antigenic epitopes of their haemagglutinin protein.
PMID: 29168676 DOI: 10.1099/jgv.0.000983
[h=1]Molecular and phylogenetic analyses of influenza B viruses isolated from pediatric inpatients in South Korea during the 2011-2012 winter season.[/h] Nam JH[SUP]1[/SUP], Song EJ[SUP]1[/SUP], Song D[SUP]1[/SUP], Espa?o E[SUP]1[/SUP], Shim SM[SUP]2,[/SUP][SUP]1[/SUP], Jeong SH[SUP]1[/SUP], Webster RG[SUP]3[/SUP], Kim WJ[SUP]4[/SUP], Kim JK[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza B virus remains a major cause of respiratory diseases worldwide. Because of limited epidemiological and genetic data, the local and global transmission patterns of influenza B virus are not fully understood. Here we report the molecular and phylogenetic characterization of 163 influenza B virus isolates from pediatric inpatients with influenza-like illness in the winter of 2011-2012 in South Korea. Analysis of haemagglutinin and neuraminidase genes of the influenza B isolates revealed that both B/Victoria (62 %) and B/Yamagata lineages (38 %) co-circulated during that influenza season, and a considerable number of the isolates carried several amino acid substitutions in the four major antigenic epitopes of their haemagglutinin protein.
PMID: 29168676 DOI: 10.1099/jgv.0.000983