Molecular characterization of a novel reassortant H7N6 subtype avian influenza virus from poultry in Eastern China, in 2016

[tetano]

Arch Virol. 2017 Jan 19. doi: 10.1007/s00705-017-3219-2. [Epub ahead of print]
[h=1]Molecular characterization of a novel reassortant H7N6 subtype avian influenza virus from poultry in Eastern China, in 2016.[/h] Wu H[SUP]1[/SUP], Lu R[SUP]2[/SUP], Peng X[SUP]1[/SUP], Peng X[SUP]1[/SUP], Chen B[SUP]1[/SUP], Cheng L[SUP]1[/SUP], Wu N[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] During the surveillance for avian influenza viruses (AIVs) in live poultry markets in Eastern China, in 2016, a novel reassortant H7N6 AIV was isolated from a chicken. Phylogenetic analysis showed that this strain received its genes from H9N2, H7N9 and H5N6 AIVs infecting poultry in China. This strain showed moderate pathogenicity in mice and was able to replicate in mice without prior adaptation. Considering that this novel reassorted H7N6 virus was isolated from poultry in this study, it is possible that chickens play an important role in the generation of novel reassorted H7N6 AIVs.


[h=4]KEYWORDS:[/h] Avian influenza viruses; Chickens; H7N6; Reassortment

PMID: 28105530 DOI: 10.1007/s00705-017-3219-2
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