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Molecular characterization of H10 subtype avian influenza viruses isolated from poultry in Eastern China

tetano

Editor, Senior Moderator
Arch Virol. 2018 Oct 9. doi: 10.1007/s00705-018-4019-z. [Epub ahead of print]
[h=1]Molecular characterization of H10 subtype avian influenza viruses isolated from poultry in Eastern China.[/h] Wu H[SUP]1[/SUP], Yang F[SUP]2[/SUP], Liu F[SUP]2[/SUP], Peng X[SUP]2[/SUP], Chen B[SUP]2[/SUP], Cheng L[SUP]2[/SUP], Lu X[SUP]2[/SUP], Yao H[SUP]2[/SUP], Wu N[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] In recent years, avian-origin H10 influenza viruses have proved capable of infecting human beings, and they pose a potential public health threat. Seven H10 avian influenza viruses (AIVs), H10N3 (n = 2), H10N7 (n = 1), and H10N8 (n = 4), were isolated from chickens in Zhejiang Province, Eastern China, during surveillance of AIVs in live poultry markets in 2016 and 2017. Phylogenetic analysis indicated that Zhejiang H10 strains received gene segments from H10, H3, and H7 viruses from birds in East Asia. Animal inoculation tests showed that these isolates have low pathogenicity in mice and can replicate in this species. Our findings suggest these H10 AIVs have the ability to adapt to chicken or other poultry, and highlight the need of long-term surveillance.


PMID: 30302582 DOI: 10.1007/s00705-018-4019-z
 
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