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Molecular genetic analysis of influenza A/H3N2 virus strains isolated in Western Siberia in the 2010-2011 epidemic season

tetano

Editor, Senior Moderator
Infect Genet Evol. 2012 Aug 16. [Epub ahead of print]
Molecular genetic analysis of influenza A/H3N2 virus strains isolated in Western Siberia in the 2010-2011 epidemic season.
Sobolev I, Kurskaya O, Susloparov I, Ilyicheva T, Shestopalov A.
Source

State Research Center of Virology and Biotechnology "Vector", Koltsovo, Novosibirsk 630559, Russia.
Abstract

Molecular genetic and antigenic features of influenza A/H3N2 virus strains isolated in Western Siberia in 2011 are similar to those of the vaccine strain A/Perth/16/2009 despite a number of unique amino-acid changes. The strains lack specific amino-acid changes in NA protein providing decrease of sensibility to NA inhibitors activity that used in medical practice. Based on phylogenic analysis of HA protein amino-acid sequences examined strains are similar to influenza A/H3N2 virus strains circulating at the moment in Eurasia.

Copyright ? 2012 Elsevier B.V. All rights reserved.

PMID:
22922296
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/22922296
 
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