Emily
Editor, Senior Moderator
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546658/
Burr T, Barton C, Doll E, Lakhotia A, Sweeney M. N-Methyl-d-Aspartate Receptor Encephalitis Associated With COVID-19 Infection in a Toddler. Pediatr Neurol. 2021;114:75-76. doi:10.1016/j.pediatrneurol.2020.10.002
Introduction
Anti–N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is characterized by mood and behavior changes, seizures, abnormal movements, autonomic instability, and encephalopathy. It occurs most commonly in young adults. A paraneoplastic association has been made with ovarian teratoma, although this is rare in children.[SUP]1[/SUP] More recently patients with anti-NMDAR encephalitis after viral infections have been reported, including herpes simplex virus (HSV), Japanese encephalitis virus, and now the 2019 novel coronavirus (SARS-CoV-2 or COVID-19).[SUP]2[/SUP][SUP], [/SUP][SUP]3[/SUP][SUP], [/SUP][SUP]4[/SUP][SUP], [/SUP][SUP]5[/SUP] We present the first pediatric patient with COVID-19–associated anti-NMDAR encephalitis.
:
Patient Description
This 23-month-old girl developed fever, fussiness, poor sleep, constipation, and decreased oral intake in July 2020. She was fully vaccinated and did not have a personal or family history of frequent infections...
Burr T, Barton C, Doll E, Lakhotia A, Sweeney M. N-Methyl-d-Aspartate Receptor Encephalitis Associated With COVID-19 Infection in a Toddler. Pediatr Neurol. 2021;114:75-76. doi:10.1016/j.pediatrneurol.2020.10.002
Introduction
Anti–N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is characterized by mood and behavior changes, seizures, abnormal movements, autonomic instability, and encephalopathy. It occurs most commonly in young adults. A paraneoplastic association has been made with ovarian teratoma, although this is rare in children.[SUP]1[/SUP] More recently patients with anti-NMDAR encephalitis after viral infections have been reported, including herpes simplex virus (HSV), Japanese encephalitis virus, and now the 2019 novel coronavirus (SARS-CoV-2 or COVID-19).[SUP]2[/SUP][SUP], [/SUP][SUP]3[/SUP][SUP], [/SUP][SUP]4[/SUP][SUP], [/SUP][SUP]5[/SUP] We present the first pediatric patient with COVID-19–associated anti-NMDAR encephalitis.
:
Patient Description
This 23-month-old girl developed fever, fussiness, poor sleep, constipation, and decreased oral intake in July 2020. She was fully vaccinated and did not have a personal or family history of frequent infections...
