tetano
Editor, Senior Moderator
Nat Commun
. 2021 Mar 26;12(1):1904.
doi: 10.1038/s41467-021-22214-z.
Hospital load and increased COVID-19 related mortality in Israel
Hagai Rossman[SUP] #[/SUP][SUP] 1 2 [/SUP], Tomer Meir[SUP] #[/SUP][SUP] 1 2 [/SUP], Jonathan Somer[SUP] 3 [/SUP], Smadar Shilo[SUP] 1 2 4 [/SUP], Rom Gutman[SUP] 3 [/SUP], Asaf Ben Arie[SUP] 5 [/SUP], Eran Segal[SUP] 6 7 [/SUP], Uri Shalit[SUP] 8 [/SUP], Malka Gorfine[SUP] 9 [/SUP]
Affiliations
Abstract
The spread of Coronavirus disease 19 (COVID-19) has led to many healthcare systems being overwhelmed by the rapid emergence of new cases. Here, we study the ramifications of hospital load due to COVID-19 morbidity on in-hospital mortality of patients with COVID-19 by analyzing records of all 22,636 COVID-19 patients hospitalized in Israel from mid-July 2020 to mid-January 2021. We show that even under moderately heavy patient load (>500 countrywide hospitalized severely-ill patients; the Israeli Ministry of Health defined 800 severely-ill patients as the maximum capacity allowing adequate treatment), in-hospital mortality rate of patients with COVID-19 significantly increased compared to periods of lower patient load (250-500 severely-ill patients): 14-day mortality rates were 22.1% (Standard Error 3.1%) higher (mid-September to mid-October) and 27.2% (Standard Error 3.3%) higher (mid-December to mid-January). We further show this higher mortality rate cannot be attributed to changes in the patient population during periods of heavier load.
. 2021 Mar 26;12(1):1904.
doi: 10.1038/s41467-021-22214-z.
Hospital load and increased COVID-19 related mortality in Israel
Hagai Rossman[SUP] #[/SUP][SUP] 1 2 [/SUP], Tomer Meir[SUP] #[/SUP][SUP] 1 2 [/SUP], Jonathan Somer[SUP] 3 [/SUP], Smadar Shilo[SUP] 1 2 4 [/SUP], Rom Gutman[SUP] 3 [/SUP], Asaf Ben Arie[SUP] 5 [/SUP], Eran Segal[SUP] 6 7 [/SUP], Uri Shalit[SUP] 8 [/SUP], Malka Gorfine[SUP] 9 [/SUP]
Affiliations
- PMID: 33771988
- DOI: 10.1038/s41467-021-22214-z
Abstract
The spread of Coronavirus disease 19 (COVID-19) has led to many healthcare systems being overwhelmed by the rapid emergence of new cases. Here, we study the ramifications of hospital load due to COVID-19 morbidity on in-hospital mortality of patients with COVID-19 by analyzing records of all 22,636 COVID-19 patients hospitalized in Israel from mid-July 2020 to mid-January 2021. We show that even under moderately heavy patient load (>500 countrywide hospitalized severely-ill patients; the Israeli Ministry of Health defined 800 severely-ill patients as the maximum capacity allowing adequate treatment), in-hospital mortality rate of patients with COVID-19 significantly increased compared to periods of lower patient load (250-500 severely-ill patients): 14-day mortality rates were 22.1% (Standard Error 3.1%) higher (mid-September to mid-October) and 27.2% (Standard Error 3.3%) higher (mid-December to mid-January). We further show this higher mortality rate cannot be attributed to changes in the patient population during periods of heavier load.