tetano
Editor, Senior Moderator
NEJM Evid
. 2023 Feb;2(2):EVIDe2200329.
doi: 10.1056/EVIDe2200329. Epub 2023 Jan 24. The Conundrum of Anticoagulation for Hospitalized Patients with Covid-19
Lauren E Merz[SUP] 1 [/SUP], Annemarie E Fogerty[SUP] 2 [/SUP]
Affiliations
Thrombosis in patients with coronavirus disease 2019 (Covid-19) is driven by complex interactions between immune, complement, fibrinolytic, endothelial, and coagulation systems.[SUP]1[/SUP] In addition to venous thromboembolism (VTE), microthrombi have also been implicated in contributing to end-organ damage, such as acute respiratory distress syndrome and kidney dysfunction, as well as to overall mortality.[SUP]1[/SUP] As available therapies, variants, and vaccines have evolved, so have reported rates of VTE attributable to Covid-19.
. 2023 Feb;2(2):EVIDe2200329.
doi: 10.1056/EVIDe2200329. Epub 2023 Jan 24. The Conundrum of Anticoagulation for Hospitalized Patients with Covid-19
Lauren E Merz[SUP] 1 [/SUP], Annemarie E Fogerty[SUP] 2 [/SUP]
Affiliations
- PMID: 38320043
- DOI: 10.1056/EVIDe2200329
Thrombosis in patients with coronavirus disease 2019 (Covid-19) is driven by complex interactions between immune, complement, fibrinolytic, endothelial, and coagulation systems.[SUP]1[/SUP] In addition to venous thromboembolism (VTE), microthrombi have also been implicated in contributing to end-organ damage, such as acute respiratory distress syndrome and kidney dysfunction, as well as to overall mortality.[SUP]1[/SUP] As available therapies, variants, and vaccines have evolved, so have reported rates of VTE attributable to Covid-19.