tetano
Editor, Senior Moderator
Neurohospitalist
. 2022 Jan;12(1):111-116.
doi: 10.1177/19418744211016709. Epub 2021 May 17.
COVID-19 Induced Miller Fisher Syndrome Presenting With Autonomic Dysfunction: A Unique Case Report and Review of Literature
Subhrajyoti Biswas[SUP] 1 [/SUP], Ritwik Ghosh[SUP] 1 [/SUP], Arpan Mandal[SUP] 1 [/SUP], Alak Pandit[SUP] 2 [/SUP], Dipayan Roy[SUP] 3 4 [/SUP], Samya Sengupta[SUP] 5 [/SUP], Kaustav De[SUP] 1 [/SUP], Bikash Chandra Swaika[SUP] 1 [/SUP], Julián Benito-León[SUP] 6 7 8 [/SUP]
Affiliations
Abstract
A plethora of neurological manifestations are associated with the 2019 coronavirus infectious disease (COVID-19). We hereby report the first case of a patient infected with SARS-CoV-2 who acutely presented with autonomic dysfunction preceding the onset of complete clinical picture of Miller Fisher syndrome. She was finally diagnosed to be a case of anti-ganglioside antibody positive post-COVID-19 Miller Fisher syndrome with dysautonomia and treated with intravenous immunoglobulin with an excellent response. We also discuss the plausible pathogenic mechanisms of COVID-19 induced Miller Fisher syndrome and furnish a review of the post-COVID-19 Miller Fisher syndrome cases reported.
Keywords: Autonomic dysfunction; COVID-19; Miller Fisher syndrome (MFS); SARS-CoV-2.
. 2022 Jan;12(1):111-116.
doi: 10.1177/19418744211016709. Epub 2021 May 17.
COVID-19 Induced Miller Fisher Syndrome Presenting With Autonomic Dysfunction: A Unique Case Report and Review of Literature
Subhrajyoti Biswas[SUP] 1 [/SUP], Ritwik Ghosh[SUP] 1 [/SUP], Arpan Mandal[SUP] 1 [/SUP], Alak Pandit[SUP] 2 [/SUP], Dipayan Roy[SUP] 3 4 [/SUP], Samya Sengupta[SUP] 5 [/SUP], Kaustav De[SUP] 1 [/SUP], Bikash Chandra Swaika[SUP] 1 [/SUP], Julián Benito-León[SUP] 6 7 8 [/SUP]
Affiliations
- PMID: 34950397
- PMCID: PMC8689536 (available on 2023-01-01)
- DOI: 10.1177/19418744211016709
Abstract
A plethora of neurological manifestations are associated with the 2019 coronavirus infectious disease (COVID-19). We hereby report the first case of a patient infected with SARS-CoV-2 who acutely presented with autonomic dysfunction preceding the onset of complete clinical picture of Miller Fisher syndrome. She was finally diagnosed to be a case of anti-ganglioside antibody positive post-COVID-19 Miller Fisher syndrome with dysautonomia and treated with intravenous immunoglobulin with an excellent response. We also discuss the plausible pathogenic mechanisms of COVID-19 induced Miller Fisher syndrome and furnish a review of the post-COVID-19 Miller Fisher syndrome cases reported.
Keywords: Autonomic dysfunction; COVID-19; Miller Fisher syndrome (MFS); SARS-CoV-2.