tetano
Editor, Senior Moderator
J Child Neurol. 2011 Oct 12. [Epub ahead of print]
Neurologic Complications of 2009 Influenza-A H1N1 Infection in Children.
Farooq O, Faden HS, Cohen ME, Ramanathan M, Barrett H, Farkas MK, Langan TJ, Yeh EA.
Source
Women and Children's Hospital of Buffalo, Department of Pediatric Neurology, University at Buffalo, and Jacobs Neurological Institute, Buffalo, NY.
Abstract
Little is known about the neurologic complications of the 2009 Influenza-A H1N1 epidemic in children. We present a retrospective analysis of children evaluated at a tertiary children's hospital who tested positive for H1N1 with neurologic complications. A total of 164 children tested positive for H1N1. Thirty-one of these patients (19%) were evaluated and discharged from the emergency department. Thirty-nine (24%) were treated in the intensive care unit, the remaining 94 (57%) were treated in medical in-patient units. Six subjects died (3.7%). Neurologic complications identified included headache, encephalitis, polyneuropathy, seizures, and malignant hyperthermia. The rate of neurologic complications in this cohort of patients who tested positive for H1N1 was 19%. The incidence of serious neurologic complications was 3%, with another 3% of patients who experienced rapid clinical deterioration and subsequently died. Our observation of neurologic complications associated with 2009 influenza-A H1N1 epidemic suggests the need for clinical vigilance during future influenza epidemics.
PMID:
21997845
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21997845
Neurologic Complications of 2009 Influenza-A H1N1 Infection in Children.
Farooq O, Faden HS, Cohen ME, Ramanathan M, Barrett H, Farkas MK, Langan TJ, Yeh EA.
Source
Women and Children's Hospital of Buffalo, Department of Pediatric Neurology, University at Buffalo, and Jacobs Neurological Institute, Buffalo, NY.
Abstract
Little is known about the neurologic complications of the 2009 Influenza-A H1N1 epidemic in children. We present a retrospective analysis of children evaluated at a tertiary children's hospital who tested positive for H1N1 with neurologic complications. A total of 164 children tested positive for H1N1. Thirty-one of these patients (19%) were evaluated and discharged from the emergency department. Thirty-nine (24%) were treated in the intensive care unit, the remaining 94 (57%) were treated in medical in-patient units. Six subjects died (3.7%). Neurologic complications identified included headache, encephalitis, polyneuropathy, seizures, and malignant hyperthermia. The rate of neurologic complications in this cohort of patients who tested positive for H1N1 was 19%. The incidence of serious neurologic complications was 3%, with another 3% of patients who experienced rapid clinical deterioration and subsequently died. Our observation of neurologic complications associated with 2009 influenza-A H1N1 epidemic suggests the need for clinical vigilance during future influenza epidemics.
PMID:
21997845
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21997845