tetano
Editor, Senior Moderator
Emerg Microbes Infect. 2019;8(1):1456-1464. doi: 10.1080/22221751.2019.1673136. [h=1]Novel reassortant of H1N1 swine influenza virus detected in pig population in Russia.[/h]
Sobolev I[SUP]1[/SUP], Kurskaya O[SUP]1[/SUP], Leonov S[SUP]2[/SUP], Kabilov M[SUP]3[/SUP], Alikina T[SUP]3[/SUP], Alekseev A[SUP]1[/SUP], Yushkov Y[SUP]2[/SUP], Saito T[SUP]4[/SUP], Uchida Y[SUP]4[/SUP], Mine J[SUP]4[/SUP], Shestopalov A[SUP]1[/SUP], Sharshov K[SUP]1[/SUP].
[h=3]Author information[/h] 1 Department of Experimental Modeling and Pathogenesis of Infectious Diseases, Federal Research Center of Fundamental and Translational Medicine , Novosibirsk , Russia. 2 Siberian Federal Scientific Centre of Agro- BioTechnologies , Krasnoobsk , Russia. 3 Institute of Chemical Biology and Fundamental Medicine , Novosibirsk , Russia. 4 Division of Transboundary Animal Disease, National Institute of Animal Health , Tsukuba , Japan.
[h=3]Abstract[/h] Pigs play an important role in interspecies transmission of the influenza virus, particularly as "mixing vessels" for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, were isolated during a surveillance of pigs from private farms in Russia from 2016 to 2017. There was a 10% identity difference between the HA and NA nucleotide sequences of isolated strains and the most phylogenetically related sequences (human influenza viruses of 1980s). Simultaneously, genome segments encoding internal proteins were found to be phylogenetically related to the A/H1N1pdm09 influenza virus. In addition, two amino acids (129-130) were deleted in the HA of A/swine/Siberia/4sw/2017 compared to that of A/swine/Siberia/1sw/2016 HA.
[h=4]KEYWORDS:[/h] H1N1; Swine; influenza; phylogeny; reassortant
PMID: 31603050 DOI: 10.1080/22221751.2019.1673136
Sobolev I[SUP]1[/SUP], Kurskaya O[SUP]1[/SUP], Leonov S[SUP]2[/SUP], Kabilov M[SUP]3[/SUP], Alikina T[SUP]3[/SUP], Alekseev A[SUP]1[/SUP], Yushkov Y[SUP]2[/SUP], Saito T[SUP]4[/SUP], Uchida Y[SUP]4[/SUP], Mine J[SUP]4[/SUP], Shestopalov A[SUP]1[/SUP], Sharshov K[SUP]1[/SUP].
[h=3]Author information[/h] 1 Department of Experimental Modeling and Pathogenesis of Infectious Diseases, Federal Research Center of Fundamental and Translational Medicine , Novosibirsk , Russia. 2 Siberian Federal Scientific Centre of Agro- BioTechnologies , Krasnoobsk , Russia. 3 Institute of Chemical Biology and Fundamental Medicine , Novosibirsk , Russia. 4 Division of Transboundary Animal Disease, National Institute of Animal Health , Tsukuba , Japan.
[h=3]Abstract[/h] Pigs play an important role in interspecies transmission of the influenza virus, particularly as "mixing vessels" for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, were isolated during a surveillance of pigs from private farms in Russia from 2016 to 2017. There was a 10% identity difference between the HA and NA nucleotide sequences of isolated strains and the most phylogenetically related sequences (human influenza viruses of 1980s). Simultaneously, genome segments encoding internal proteins were found to be phylogenetically related to the A/H1N1pdm09 influenza virus. In addition, two amino acids (129-130) were deleted in the HA of A/swine/Siberia/4sw/2017 compared to that of A/swine/Siberia/1sw/2016 HA.
[h=4]KEYWORDS:[/h] H1N1; Swine; influenza; phylogeny; reassortant
PMID: 31603050 DOI: 10.1080/22221751.2019.1673136