Emily
Editor, Senior Moderator
https://www.nature.com/articles/s41422-021-00603-9
Hoffmann, M., Pöhlmann, S. Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1. Cell Res 32, 1–2 (2022). https://doi.org/10.1038/s41422-021-00603-9
The interaction of the SARS-CoV-2 spike protein with the cellular receptor ACE2 is believed to be essential for viral entry into host cells. In a recent paper published in Cell Research, Gu and colleagues report that ASGR1 and KREMEN1 can also serve as SARS-CoV-2 receptors and might impact viral target cell range and antibody-mediated neutralization.
Hoffmann, M., Pöhlmann, S. Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1. Cell Res 32, 1–2 (2022). https://doi.org/10.1038/s41422-021-00603-9
The interaction of the SARS-CoV-2 spike protein with the cellular receptor ACE2 is believed to be essential for viral entry into host cells. In a recent paper published in Cell Research, Gu and colleagues report that ASGR1 and KREMEN1 can also serve as SARS-CoV-2 receptors and might impact viral target cell range and antibody-mediated neutralization.