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NPJ Vaccines . Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines

tetano

Editor, Senior Moderator
NPJ Vaccines


. 2025 Jan 14;10(1):8.
doi: 10.1038/s41541-025-01063-7. Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines

Rodrigo Prado Martins[SUP] 1 [/SUP], Daniel Marc[SUP] 2 [/SUP], Pierre Germon[SUP] 2 [/SUP], Sascha Trapp[SUP] 2 [/SUP], Ignacio Caballero-Posadas[SUP] 2 [/SUP]



Affiliations
Abstract

Influenza, a major "One Health" threat, has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review explores general aspects of influenza A virus (IAV) biology, its interactions with mammalian hosts, and discusses the key considerations for developing vaccines to prevent or curtail IAV infection in the bovine mammary gland and its spread through milk.


 
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