tetano
Editor, Senior Moderator
Obesity (Silver Spring)
. 2020 Jul 31.
doi: 10.1002/oby.22979. Online ahead of print.
Overweight and obesity are risks factors of severe illness in patients with COVID-19
Jian Wang[SUP] 1 [/SUP], Li Zhu[SUP] 2 [/SUP], Longgen Liu[SUP] 3 [/SUP], Xiang-An Zhao[SUP] 4 [/SUP], Zhaoping Zhang[SUP] 1 [/SUP], Leyang Xue[SUP] 5 [/SUP], Xuebing Yan[SUP] 6 [/SUP], Songping Huang[SUP] 7 [/SUP], Yang Li[SUP] 8 [/SUP], Juan Cheng[SUP] 9 [/SUP], Biao Zhang[SUP] 10 [/SUP], Tianmin Xu[SUP] 4 [/SUP], Chunyang Li[SUP] 6 [/SUP], Fang Ji[SUP] 6 [/SUP], Fang Ming[SUP] 7 [/SUP], Yun Zhao[SUP] 11 [/SUP], Huaping Shao[SUP] 12 [/SUP], Dawen Sang[SUP] 9 [/SUP], Haiyan Zhao[SUP] 12 [/SUP], Xinying Guan[SUP] 13 [/SUP], Xiaobing Chen[SUP] 14 [/SUP], Yuxin Chen[SUP] 15 [/SUP], Rahma Issa[SUP] 16 [/SUP], Jie Wei[SUP] 16 [/SUP], Rui Huang[SUP] 1 [/SUP], Chuanwu Zhu[SUP] 2 [/SUP], Chao Wu[SUP] 1 [/SUP]
Affiliations
Abstract
Objective: We aimed to observe the clinical characteristics of coronavirus disease 2019 (COVID-19) patients with overweight and obesity.
Methods: Consecutive COVID-19 patients from 10 hospitals of Jiangsu province, China were enrolled.
Results: 297 COVID-19 patients were included. 39.39% and 13.47% of patients were overweight and obese, respectively. The proportions of bilateral pneumonia (92.50% vs. 73.57%, P=0.033) and type 2 diabetes (17.50% vs. 3.57%, P=0.006) were higher in patients with obesity than lean patients. The proportions of severe illness in patients with overweight (12.82% vs. 2.86%, P=0.006) and obesity (25.00% vs. 2.86%, P<0.001) were significantly higher than lean patients. More patients with obesity developed respiratory failure (20.00% vs. 2.86%, P<0.001) and acute respiratory distress syndrome (5.00% vs. 0%, P=0.024) than lean patients. The median days of hospitalization were longer in patients with obesity than lean patients (17.00 days vs. 14.00 days, P=0.029). Overweight (OR 4.222, 95%CI 1.322-13.476, P=0.015) and obesity (OR 9.216, 95% CI 2.581-32.903, P=0.001) were independent risk factors of severe illness. Obesity (HR 6.607, 95% CI 1.955-22.329, P=0.002) was an independent risk factor of respiratory failure.
Conclusion: Overweight and obesity were independent risk factors of severe illness in COVID-19 patients. More attention should be paid to these patients.
Keywords: coronavirus disease 2019; obesity; overweight; severe illness.
. 2020 Jul 31.
doi: 10.1002/oby.22979. Online ahead of print.
Overweight and obesity are risks factors of severe illness in patients with COVID-19
Jian Wang[SUP] 1 [/SUP], Li Zhu[SUP] 2 [/SUP], Longgen Liu[SUP] 3 [/SUP], Xiang-An Zhao[SUP] 4 [/SUP], Zhaoping Zhang[SUP] 1 [/SUP], Leyang Xue[SUP] 5 [/SUP], Xuebing Yan[SUP] 6 [/SUP], Songping Huang[SUP] 7 [/SUP], Yang Li[SUP] 8 [/SUP], Juan Cheng[SUP] 9 [/SUP], Biao Zhang[SUP] 10 [/SUP], Tianmin Xu[SUP] 4 [/SUP], Chunyang Li[SUP] 6 [/SUP], Fang Ji[SUP] 6 [/SUP], Fang Ming[SUP] 7 [/SUP], Yun Zhao[SUP] 11 [/SUP], Huaping Shao[SUP] 12 [/SUP], Dawen Sang[SUP] 9 [/SUP], Haiyan Zhao[SUP] 12 [/SUP], Xinying Guan[SUP] 13 [/SUP], Xiaobing Chen[SUP] 14 [/SUP], Yuxin Chen[SUP] 15 [/SUP], Rahma Issa[SUP] 16 [/SUP], Jie Wei[SUP] 16 [/SUP], Rui Huang[SUP] 1 [/SUP], Chuanwu Zhu[SUP] 2 [/SUP], Chao Wu[SUP] 1 [/SUP]
Affiliations
- PMID: 32735706
- DOI: 10.1002/oby.22979
Abstract
Objective: We aimed to observe the clinical characteristics of coronavirus disease 2019 (COVID-19) patients with overweight and obesity.
Methods: Consecutive COVID-19 patients from 10 hospitals of Jiangsu province, China were enrolled.
Results: 297 COVID-19 patients were included. 39.39% and 13.47% of patients were overweight and obese, respectively. The proportions of bilateral pneumonia (92.50% vs. 73.57%, P=0.033) and type 2 diabetes (17.50% vs. 3.57%, P=0.006) were higher in patients with obesity than lean patients. The proportions of severe illness in patients with overweight (12.82% vs. 2.86%, P=0.006) and obesity (25.00% vs. 2.86%, P<0.001) were significantly higher than lean patients. More patients with obesity developed respiratory failure (20.00% vs. 2.86%, P<0.001) and acute respiratory distress syndrome (5.00% vs. 0%, P=0.024) than lean patients. The median days of hospitalization were longer in patients with obesity than lean patients (17.00 days vs. 14.00 days, P=0.029). Overweight (OR 4.222, 95%CI 1.322-13.476, P=0.015) and obesity (OR 9.216, 95% CI 2.581-32.903, P=0.001) were independent risk factors of severe illness. Obesity (HR 6.607, 95% CI 1.955-22.329, P=0.002) was an independent risk factor of respiratory failure.
Conclusion: Overweight and obesity were independent risk factors of severe illness in COVID-19 patients. More attention should be paid to these patients.
Keywords: coronavirus disease 2019; obesity; overweight; severe illness.