tetano
Editor, Senior Moderator
Ocul Immunol Inflamm
. 2022 Feb 24;1-8.
doi: 10.1080/09273948.2022.2032195. Online ahead of print.
Sarcoid-like Uveitis with or without Tubulointerstitial Nephritis during COVID-19
Hilal Eser-Ozturk[SUP] 1 [/SUP], Tugba Izci Duran[SUP] 2 [/SUP], Ozlem Aydog[SUP] 3 [/SUP], Yuksel Sullu[SUP] 1 [/SUP]
Affiliations
Abstract
Purpose: To report sarcoid-like uveitis with or without tubulointerstitial nephritis (TIN) during coronavirus disease 2019 (COVID-19) and to discuss diagnostic evaluation and treatment.
Methods: Detailed information on the subject's demographics, medical history, ophthalmic examination findings, and laboratory results were obtained from medical records. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) images were evaluated.
Results: All seven patients aged between 8 and 17 had bilateral granulomatous panuveitis. TIN preceded in four patients. Thorax computed tomography of patient 1 was found to be compatible with COVID-19, patients 2 and 3 were in contact with Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive parents, patients 4 and 5 were found to be SARS-CoV-2 PCR positive, and patients 6 and 7 were positive for SARS-CoV-2 IgG antibodies. ICGA revealed hypofluorescent dots in six patients. Intraocular inflammation was controlled with corticosteroid and/or immunomodulatory therapy. Visual acuity was maintained or improved in all.
Conclusion: SARS-CoV-2 infection may be related to sarcoid-like uveitis and acute tubulointerstitial nephritis.
Keywords: Acute kidney injury; COVID-19; SARS-CoV-2; TINU; granuloma; granulomatous uveitis; sarcoid-like uveitis; tubulointerstitial nephritis.
. 2022 Feb 24;1-8.
doi: 10.1080/09273948.2022.2032195. Online ahead of print.
Sarcoid-like Uveitis with or without Tubulointerstitial Nephritis during COVID-19
Hilal Eser-Ozturk[SUP] 1 [/SUP], Tugba Izci Duran[SUP] 2 [/SUP], Ozlem Aydog[SUP] 3 [/SUP], Yuksel Sullu[SUP] 1 [/SUP]
Affiliations
- PMID: 35201954
- DOI: 10.1080/09273948.2022.2032195
Abstract
Purpose: To report sarcoid-like uveitis with or without tubulointerstitial nephritis (TIN) during coronavirus disease 2019 (COVID-19) and to discuss diagnostic evaluation and treatment.
Methods: Detailed information on the subject's demographics, medical history, ophthalmic examination findings, and laboratory results were obtained from medical records. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) images were evaluated.
Results: All seven patients aged between 8 and 17 had bilateral granulomatous panuveitis. TIN preceded in four patients. Thorax computed tomography of patient 1 was found to be compatible with COVID-19, patients 2 and 3 were in contact with Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive parents, patients 4 and 5 were found to be SARS-CoV-2 PCR positive, and patients 6 and 7 were positive for SARS-CoV-2 IgG antibodies. ICGA revealed hypofluorescent dots in six patients. Intraocular inflammation was controlled with corticosteroid and/or immunomodulatory therapy. Visual acuity was maintained or improved in all.
Conclusion: SARS-CoV-2 infection may be related to sarcoid-like uveitis and acute tubulointerstitial nephritis.
Keywords: Acute kidney injury; COVID-19; SARS-CoV-2; TINU; granuloma; granulomatous uveitis; sarcoid-like uveitis; tubulointerstitial nephritis.