tetano
Editor, Senior Moderator
Ocul Immunol Inflamm
. 2020 Sep 18;1-4.
doi: 10.1080/09273948.2020.1799037. Online ahead of print.
SARS-CoV-2 Targeting the Retina: Host-virus Interaction and Possible Mechanisms of Viral Tropism
Camila Saggioro de Figueiredo[SUP] 1 [/SUP], ?caro Raony[SUP] 1 2 [/SUP], Elizabeth Giestal-de-Araujo[SUP] 1 3 [/SUP]
Affiliations
Abstract
Background: Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 10 (SARS-CoV-2). Recent studies demonstrated not only retinal impairments but also detected SARS-CoV-2 in the retina of patients with COVID-19.
Purpose: This letter discusses the retinal tropism of SARS-CoV-2, describing possible routes for this coronavirus to reach the retina and cellular mechanisms involved in the retinal cell infection.
Conclusions: Determining how SARS-CoV-2 can affect the retinal tissue is essential for the development of new therapeutic strategies and preventive measures, as well as for understanding the possible relationship between COVID-19 damage to the retina and to the brain.
Keywords: Central nervous system; Covid-19; SARS-CoV-2; eye; ophthalmology; retina.
. 2020 Sep 18;1-4.
doi: 10.1080/09273948.2020.1799037. Online ahead of print.
SARS-CoV-2 Targeting the Retina: Host-virus Interaction and Possible Mechanisms of Viral Tropism
Camila Saggioro de Figueiredo[SUP] 1 [/SUP], ?caro Raony[SUP] 1 2 [/SUP], Elizabeth Giestal-de-Araujo[SUP] 1 3 [/SUP]
Affiliations
- PMID: 32946292
- DOI: 10.1080/09273948.2020.1799037
Abstract
Background: Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 10 (SARS-CoV-2). Recent studies demonstrated not only retinal impairments but also detected SARS-CoV-2 in the retina of patients with COVID-19.
Purpose: This letter discusses the retinal tropism of SARS-CoV-2, describing possible routes for this coronavirus to reach the retina and cellular mechanisms involved in the retinal cell infection.
Conclusions: Determining how SARS-CoV-2 can affect the retinal tissue is essential for the development of new therapeutic strategies and preventive measures, as well as for understanding the possible relationship between COVID-19 damage to the retina and to the brain.
Keywords: Central nervous system; Covid-19; SARS-CoV-2; eye; ophthalmology; retina.