tetano
Editor, Senior Moderator
Open Forum Infect Dis
. 2020 Sep 3;7(10)
faa407.
doi: 10.1093/ofid/ofaa407. eCollection 2020 Oct.
Association of Early Nasopharyngeal Immune Markers With COVID-19 Clinical Outcome: Predictive Value of CCL2/MCP-1
Beatriz Sierra[SUP] 1 [/SUP], Ana B P?rez[SUP] 1 [/SUP], Eglis Aguirre[SUP] 1 [/SUP], Claudia Bracho[SUP] 1 [/SUP], Odalys Vald?s[SUP] 2 [/SUP], Narciso Jimenez[SUP] 3 [/SUP], Waldemar Baldoquin[SUP] 4 [/SUP], Guelsys Gonzalez[SUP] 2 [/SUP], Lilia M Ortega[SUP] 5 [/SUP], Maria C Montalvo[SUP] 6 [/SUP], Sonia Resik[SUP] 7 [/SUP], Delmis Alvarez[SUP] 8 [/SUP], Maria G Guzm?n[SUP] 9 [/SUP]
Affiliations
Abstract
Early recognition of severe forms of coronavirus disease 2019 (COVID-19) is essential for an opportune and effective intervention, reducing life-risking complications. An altered inflammatory immune response seems to be associated with COVID-19's pathogenesis and progression to severity. Here we demonstrate the utility of early nasopharyngeal swab samples for detection of the early expression of immune markers and the potential value of CCL2/MCP-1 in predicting disease outcome.
Keywords: COVID-19; chemokines; cytokines; inflammation; prognostic biomarkers.
. 2020 Sep 3;7(10)
faa407.doi: 10.1093/ofid/ofaa407. eCollection 2020 Oct.
Association of Early Nasopharyngeal Immune Markers With COVID-19 Clinical Outcome: Predictive Value of CCL2/MCP-1
Beatriz Sierra[SUP] 1 [/SUP], Ana B P?rez[SUP] 1 [/SUP], Eglis Aguirre[SUP] 1 [/SUP], Claudia Bracho[SUP] 1 [/SUP], Odalys Vald?s[SUP] 2 [/SUP], Narciso Jimenez[SUP] 3 [/SUP], Waldemar Baldoquin[SUP] 4 [/SUP], Guelsys Gonzalez[SUP] 2 [/SUP], Lilia M Ortega[SUP] 5 [/SUP], Maria C Montalvo[SUP] 6 [/SUP], Sonia Resik[SUP] 7 [/SUP], Delmis Alvarez[SUP] 8 [/SUP], Maria G Guzm?n[SUP] 9 [/SUP]
Affiliations
- PMID: 33123608
- PMCID: PMC7499702
- DOI: 10.1093/ofid/ofaa407
Abstract
Early recognition of severe forms of coronavirus disease 2019 (COVID-19) is essential for an opportune and effective intervention, reducing life-risking complications. An altered inflammatory immune response seems to be associated with COVID-19's pathogenesis and progression to severity. Here we demonstrate the utility of early nasopharyngeal swab samples for detection of the early expression of immune markers and the potential value of CCL2/MCP-1 in predicting disease outcome.
Keywords: COVID-19; chemokines; cytokines; inflammation; prognostic biomarkers.