tetano
Editor, Senior Moderator
Open Forum Infect Dis
. 2021 Aug 9;8(9)
fab415.
doi: 10.1093/ofid/ofab415. eCollection 2021 Sep.
Nonpharmaceutical Interventions Remain Essential to Reducing Coronavirus Disease 2019 Burden Even in a Well-Vaccinated Society: A Modeling Study
Tomás M León[SUP] 1 [/SUP], Jason Vargo[SUP] 1 2 [/SUP], Erica S Pan[SUP] 1 [/SUP], Seema Jain[SUP] 1 [/SUP], Priya B Shete[SUP] 1 3 [/SUP]
Affiliations
Abstract
Vaccination and nonpharmaceutical interventions (NPIs) reduce transmission of severe acute respiratory syndrome coronavirus 2 infection, but their effectiveness depends on coverage and adherence levels. We used scenario modeling to evaluate their effects on cases and deaths averted and herd immunity. NPIs and vaccines worked synergistically in different parts of the pandemic to reduce disease burden.
Keywords: COVID-19; California; NPIs; herd immunity; mathematical modeling; vaccination.
. 2021 Aug 9;8(9)
fab415.doi: 10.1093/ofid/ofab415. eCollection 2021 Sep.
Nonpharmaceutical Interventions Remain Essential to Reducing Coronavirus Disease 2019 Burden Even in a Well-Vaccinated Society: A Modeling Study
Tomás M León[SUP] 1 [/SUP], Jason Vargo[SUP] 1 2 [/SUP], Erica S Pan[SUP] 1 [/SUP], Seema Jain[SUP] 1 [/SUP], Priya B Shete[SUP] 1 3 [/SUP]
Affiliations
- PMID: 34514021
- PMCID: PMC8419741
- DOI: 10.1093/ofid/ofab415
Abstract
Vaccination and nonpharmaceutical interventions (NPIs) reduce transmission of severe acute respiratory syndrome coronavirus 2 infection, but their effectiveness depends on coverage and adherence levels. We used scenario modeling to evaluate their effects on cases and deaths averted and herd immunity. NPIs and vaccines worked synergistically in different parts of the pandemic to reduce disease burden.
Keywords: COVID-19; California; NPIs; herd immunity; mathematical modeling; vaccination.