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Open Forum Infect Dis . Prospective Clinical Assessments of Hospitalized Patients With Positive SARS-CoV-2 PCR Tests for Necessity of Isolation

tetano

Editor, Senior Moderator
Open Forum Infect Dis


. 2021 Apr 16;8(7):ofab194.
doi: 10.1093/ofid/ofab194. eCollection 2021 Jul.
Prospective Clinical Assessments of Hospitalized Patients With Positive SARS-CoV-2 PCR Tests for Necessity of Isolation


Chanu Rhee[SUP] 1 2 3 [/SUP], Meghan A Baker[SUP] 1 2 3 4 [/SUP], Sanjat Kanjilal[SUP] 1 2 [/SUP], Robert Tucker[SUP] 3 [/SUP], Vineeta Vaidya[SUP] 3 [/SUP], Amy Badwaik[SUP] 3 [/SUP], Elizabeth Mermel Blaeser[SUP] 3 [/SUP], Cassie Coughlin[SUP] 4 [/SUP], Jennifer Elloyan[SUP] 3 [/SUP], Candace Hsieh[SUP] 4 [/SUP], Meghan Holtzman[SUP] 3 [/SUP], Ofelia Solem[SUP] 3 [/SUP], Michael Klompas[SUP] 1 2 3 [/SUP]



Affiliations

Abstract

We prospectively assessed 536 hospitalized patients with positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction tests for infectiousness based on symptoms, cycle thresholds, and SARS-CoV-2 history, with repeat testing and serologies in select cases. One hundred forty-eight (28%) patients were deemed noninfectious, most with evidence of prior infection, and managed on standard precautions without evidence of transmission.

Keywords: COVID-19; SARS-CoV-2; isolation; polymerase chain reaction; transmission-based precautions.
 
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