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Open Forum Infect Dis . Risk of Reinfection and Incidence of Chronic Symptoms After SARS-CoV-2 Infections

tetano

Editor, Senior Moderator
Open Forum Infect Dis


. 2024 Oct 15;11(10):ofae608.
doi: 10.1093/ofid/ofae608. eCollection 2024 Oct. Risk of Reinfection and Incidence of Chronic Symptoms After SARS-CoV-2 Infections

Liam Golding[SUP] 1 2 [/SUP], Allison W Watts[SUP] 1 2 [/SUP], Mark Pitblado[SUP] 1 [/SUP], Felicity Clemens[SUP] 3 [/SUP], Marina Viñeta Paramo[SUP] 1 2 [/SUP], Jacob Shew[SUP] 1 2 [/SUP], Michael A Irvine[SUP] 3 [/SUP], Bahaa Abu-Raya[SUP] 1 2 4 [/SUP], David M Goldfarb[SUP] 1 5 [/SUP], Louise C Mâsse[SUP] 1 6 [/SUP], Pascal M Lavoie[SUP] 1 2 [/SUP]



Affiliations
Abstract

This study showed that a severe acute respiratory syndrome coronavirus 2 infection reduced the risk of reinfection among vaccinated individuals by 0.50 (95% CI, 0.39-0.64) over a 1-year period, after accounting for unreported infections using avidity-based serology. Reciprocally, chronic symptoms increased from a baseline of 21% (95% CI, 16%-28%) among infection-naïve individuals to 43% (95% CI, 30%-61%) in reinfected individuals.

Keywords: COVID-19; Omicron; SARS-CoV-2; post-COVID symptoms; serology.

 
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