tetano
Editor, Senior Moderator
Open Forum Infect Dis
. 2020 Jun 20;7(7)
faa243.
doi: 10.1093/ofid/ofaa243. eCollection 2020 Jul.
SARS-CoV-2 Screening Test for Japanese Returnees From Wuhan, China, January 2020
Satoshi Kutsuna[SUP] 1 [/SUP], Tadaki Suzuki[SUP] 2 [/SUP], Kayoko Hayakawa[SUP] 1 [/SUP], Shinya Tsuzuki[SUP] 3 [/SUP], Yusuke Asai[SUP] 3 [/SUP], Tetsuya Suzuki[SUP] 1 [/SUP], Satoshi Ide[SUP] 1 [/SUP], Keiji Nakamura[SUP] 1 [/SUP], Yuki Moriyama[SUP] 1 [/SUP], Noriko Kinoshita[SUP] 1 [/SUP], Naoto Hosokawa[SUP] 4 [/SUP], Ryosuke Osawa[SUP] 4 [/SUP], Ryosuke Yamamuro[SUP] 4 [/SUP], Yutaro Akiyama[SUP] 1 [/SUP], Yusuke Miyazato[SUP] 1 [/SUP], Hidetoshi Nomoto[SUP] 1 [/SUP], Takato Nakamoto[SUP] 1 [/SUP], Masayuki Ota[SUP] 1 [/SUP], Sho Saito[SUP] 1 [/SUP], Masahiro Ishikane[SUP] 1 [/SUP], Shinichiro Morioka[SUP] 1 [/SUP], Kei Yamamoto[SUP] 1 [/SUP], Mugen Ujiie[SUP] 1 [/SUP], Mari Terada[SUP] 1 [/SUP], Fukumi Nakamura-Uchiyama[SUP] 5 [/SUP], Toshinori Sahara[SUP] 5 [/SUP], Masahiro Sano[SUP] 6 [/SUP], Akifumi Imamura[SUP] 7 [/SUP], Noritaka Sekiya[SUP] 8 [/SUP], Kazuaki Fukushima[SUP] 7 [/SUP], Akihiko Kawana[SUP] 9 [/SUP], Yuji Fujikura[SUP] 9 [/SUP], Tomoya Sano[SUP] 9 [/SUP], Ryohei Suematsu[SUP] 9 [/SUP], Naoya Sakamoto[SUP] 10 [/SUP], Kaoru Nagata[SUP] 11 [/SUP], Tomoyuki Kato[SUP] 11 [/SUP], Harutaka Katano[SUP] 2 [/SUP], Takaji Wakita[SUP] 2 [/SUP], Haruhito Sugiyama[SUP] 12 [/SUP], Norihiro Kokudo[SUP] 12 [/SUP], Norio Ohmagari[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) was found to be the causative microorganism of coronavirus disease 2019 (COVID-19), which started to spread in Wuhan, China. This study was to evaluate the effectiveness of questionnaire, symptoms-based screening, and polymerase chain reaction (PCR) screening of returnees from COVID-19-endemic areas on a chartered flight, to examine the proportion of infected persons and the proportion of asymptomatic persons among infected persons who returned from Wuhan.
Methods: A retrospective cohort study was done in 7 tertiary medical institutions in Japan. A total of 566 Japanese who returned from Wuhan participated in the study.
Results: Overall, 11 of the 566 passengers had a positive SARS-CoV-2 PCR result for pharyngeal swabs and 6 were asymptomatic. Only fever differed between SARS-CoV-2-positive and -negative individuals (P < .043). Six of the 11 PCR-positive individuals were asymptomatic; 4 remained positive on day 10, and 1 asymptomatic person tested positive up to day 27. Two of the 11 were negative on the first PCR test and positive on the second.
Conclusions: Our results will be important insights on screening returnees from locked-down cities, as well as providing important data on the proportion of asymptomatic individuals infected with SARS-CoV-2. A 13-day observation period and a second round of PCR may be effective to screen patients, including asymptomatic infections.
Keywords: COVID-19; SARS-CoV-2; Wuhan; lockdown; returnees.
. 2020 Jun 20;7(7)
faa243.doi: 10.1093/ofid/ofaa243. eCollection 2020 Jul.
SARS-CoV-2 Screening Test for Japanese Returnees From Wuhan, China, January 2020
Satoshi Kutsuna[SUP] 1 [/SUP], Tadaki Suzuki[SUP] 2 [/SUP], Kayoko Hayakawa[SUP] 1 [/SUP], Shinya Tsuzuki[SUP] 3 [/SUP], Yusuke Asai[SUP] 3 [/SUP], Tetsuya Suzuki[SUP] 1 [/SUP], Satoshi Ide[SUP] 1 [/SUP], Keiji Nakamura[SUP] 1 [/SUP], Yuki Moriyama[SUP] 1 [/SUP], Noriko Kinoshita[SUP] 1 [/SUP], Naoto Hosokawa[SUP] 4 [/SUP], Ryosuke Osawa[SUP] 4 [/SUP], Ryosuke Yamamuro[SUP] 4 [/SUP], Yutaro Akiyama[SUP] 1 [/SUP], Yusuke Miyazato[SUP] 1 [/SUP], Hidetoshi Nomoto[SUP] 1 [/SUP], Takato Nakamoto[SUP] 1 [/SUP], Masayuki Ota[SUP] 1 [/SUP], Sho Saito[SUP] 1 [/SUP], Masahiro Ishikane[SUP] 1 [/SUP], Shinichiro Morioka[SUP] 1 [/SUP], Kei Yamamoto[SUP] 1 [/SUP], Mugen Ujiie[SUP] 1 [/SUP], Mari Terada[SUP] 1 [/SUP], Fukumi Nakamura-Uchiyama[SUP] 5 [/SUP], Toshinori Sahara[SUP] 5 [/SUP], Masahiro Sano[SUP] 6 [/SUP], Akifumi Imamura[SUP] 7 [/SUP], Noritaka Sekiya[SUP] 8 [/SUP], Kazuaki Fukushima[SUP] 7 [/SUP], Akihiko Kawana[SUP] 9 [/SUP], Yuji Fujikura[SUP] 9 [/SUP], Tomoya Sano[SUP] 9 [/SUP], Ryohei Suematsu[SUP] 9 [/SUP], Naoya Sakamoto[SUP] 10 [/SUP], Kaoru Nagata[SUP] 11 [/SUP], Tomoyuki Kato[SUP] 11 [/SUP], Harutaka Katano[SUP] 2 [/SUP], Takaji Wakita[SUP] 2 [/SUP], Haruhito Sugiyama[SUP] 12 [/SUP], Norihiro Kokudo[SUP] 12 [/SUP], Norio Ohmagari[SUP] 1 [/SUP]
Affiliations
- PMID: 32754627
- PMCID: PMC7337761
- DOI: 10.1093/ofid/ofaa243
Abstract
Background: Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) was found to be the causative microorganism of coronavirus disease 2019 (COVID-19), which started to spread in Wuhan, China. This study was to evaluate the effectiveness of questionnaire, symptoms-based screening, and polymerase chain reaction (PCR) screening of returnees from COVID-19-endemic areas on a chartered flight, to examine the proportion of infected persons and the proportion of asymptomatic persons among infected persons who returned from Wuhan.
Methods: A retrospective cohort study was done in 7 tertiary medical institutions in Japan. A total of 566 Japanese who returned from Wuhan participated in the study.
Results: Overall, 11 of the 566 passengers had a positive SARS-CoV-2 PCR result for pharyngeal swabs and 6 were asymptomatic. Only fever differed between SARS-CoV-2-positive and -negative individuals (P < .043). Six of the 11 PCR-positive individuals were asymptomatic; 4 remained positive on day 10, and 1 asymptomatic person tested positive up to day 27. Two of the 11 were negative on the first PCR test and positive on the second.
Conclusions: Our results will be important insights on screening returnees from locked-down cities, as well as providing important data on the proportion of asymptomatic individuals infected with SARS-CoV-2. A 13-day observation period and a second round of PCR may be effective to screen patients, including asymptomatic infections.
Keywords: COVID-19; SARS-CoV-2; Wuhan; lockdown; returnees.