Open Forum Infect Dis . Time Course of Neutralizing Antibody in Health Care Workers With Mild or Asymptomatic COVID-19 Infection

[tetano]

Open Forum Infect Dis


. 2021 Jun 12;8(7)fab312.
doi: 10.1093/ofid/ofab312. eCollection 2021 Jul.
Time Course of Neutralizing Antibody in Health Care Workers With Mild or Asymptomatic COVID-19 Infection


Ilaria Vicenti[SUP] 1 [/SUP], Francesca Gatti[SUP] 2 [/SUP], Renzo Scaggiante[SUP] 3 [/SUP], Adele Boccuto[SUP] 1 [/SUP], Eliana Modolo[SUP] 3 [/SUP], Daniela Zago[SUP] 2 [/SUP], Monica Basso[SUP] 2 [/SUP], Filippo Dragoni[SUP] 1 [/SUP], Niccolo' Bartolini[SUP] 1 [/SUP], Maurizio Zazzi[SUP] 1 [/SUP], Saverio Giuseppe Parisi[SUP] 2 [/SUP]



Affiliations

• PMID: 34295945
• PMCID: PMC8291533
• DOI: 10.1093/ofid/ofab312

Abstract

We describe the time course of neutralizing antibody (NtAb) titer in a cohort of health care workers with mild or asymptomatic severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection. NtAb levels decreased over time; however, serum neutralizing activity remained detectable after a median of 7 months from SARS-CoV-2 diagnosis in the majority of cases.

Keywords: SARS-CoV-2; follow-up; health care workers; mild or asymptomatic infection; neutralizing antibody titer.