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Open Forum Infect Dis . Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity

tetano

Editor, Senior Moderator
Open Forum Infect Dis


. 2022 Jan 5;9(3):ofab664.
doi: 10.1093/ofid/ofab664. eCollection 2022 Mar.
Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity


Melisa M Shah[SUP] 1 2 [/SUP], Mohammad Ata Ur Rasheed[SUP] 1 [/SUP], Jennifer L Harcourt[SUP] 1 [/SUP], Glen R Abedi[SUP] 1 [/SUP], Megan M Stumpf[SUP] 1 [/SUP], Hannah L Kirking[SUP] 1 [/SUP], Azaibi Tamin[SUP] 1 [/SUP], Lisa Mills[SUP] 1 [/SUP], Madeleine Armstrong[SUP] 3 [/SUP], Phillip P Salvatore[SUP] 1 2 [/SUP], Krishna Surasi[SUP] 2 4 [/SUP], Sarah E Scott[SUP] 5 [/SUP], Marie E Killerby[SUP] 1 [/SUP], Melissa Briggs-Hagen[SUP] 1 [/SUP], Sharon Saydah[SUP] 1 [/SUP], Jacqueline E Tate[SUP] 1 [/SUP], Alicia M Fry[SUP] 1 [/SUP], Aron J Hall[SUP] 1 [/SUP], Natalie J Thornburg[SUP] 1 [/SUP], Claire M Midgley[SUP] 1 [/SUP], COVID-19 Follow-Up Investigation Team



Collaborators, Affiliations

Abstract

We quantify antibody and memory B-cell responses to severe acute respiratory syndrome coronavirus 2 at 6 and 12 months postinfection among 7 unvaccinated US coronavirus disease 2019 cases. All had detectable S-specific memory B cells and immunoglobulin G at both time points, with geometric mean titers of 117.2 BAU/mL and 84.0 BAU/mL at 6 and 12 months, respectively.

Keywords: COVID-19; SARS-CoV-2 infection; immunity; memory B cells.
 
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