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Oseltamivir (Tamiflu)-induced Bilateral Ciliochoroidal Effusion and Angle Closure Glaucoma: What Type of Idiosyncratic Reaction?

tetano

Editor, Senior Moderator
J Ophthalmic Vis Res. 2017 Oct-Dec;12(4):434-436. doi: 10.4103/jovr.jovr_200_15.
[h=1]Oseltamivir (Tamiflu)-induced Bilateral Ciliochoroidal Effusion and Angle Closure Glaucoma: What Type of Idiosyncratic Reaction?[/h] Yazdani S[SUP]1,[/SUP][SUP]2[/SUP], Esfandiari H[SUP]2[/SUP], Safi S[SUP]2[/SUP], Fatemi A[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]PURPOSE:[/h] To report a case of bilateral acute angle closure glaucoma after one dose of oseltamivir 75 mg.
[h=4]CASE REPORT:[/h] A 37-year-old man with a history of influenza developed high intraocular pressure and uniformly shallow anterior chamber in both eyes, 5 hours after the first dose of oseltamivir 75 mg. The condition was managed successfully with topical cycloplegic and systemic/topical antiglaucoma medications.
[h=4]CONCLUSION:[/h] Since a presumed idiosyncratic reaction developed right after the first dose of the medication, it challenges the common concept of adaptive immune system involvement in this type of reaction in medication-related ciliochoroidal effusion.


[h=4]KEYWORDS:[/h] Ciliochoroidal Effusion; Idiosyncratic Reaction; Oseltamivir

PMID: 29090056 PMCID: PMC5644413 DOI: 10.4103/jovr.jovr_200_15
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