tetano
Editor, Senior Moderator
Pan Afr Med J
. 2021 Nov 18;40:169.
doi: 10.11604/pamj.2021.40.169.31223. eCollection 2021.
Increasing incidence of lung transplantation in patients with post-COVID-19 pulmonary fibrosis
Rumi Khajotia[SUP] 1 [/SUP]
Affiliations
Abstract
Twenty months into the COVID-19 pandemic, we are still learning about the various long-term consequences of COVID-19 infection. While many patients do recover with minimal long-term consequences, some patients develop irreversible parenchymal and interstitial lung damage leading to diffuse pulmonary fibrosis. Unfortunately, these are some of the consequences of post-SARS-CoV-2 infection which thousands more people around the world will experience and which will outlast the pandemic for a long time to come. It is now being observed at various leading medical centres around the world that lung transplantation may be the only meaningful treatment available to a select group of patients experiencing serious lung damage and non-resolving COVID-19-associated respiratory failure, resulting from the triad of coronavirus infection, a hyper-inflammatory immune response to it and the inability of the human body to repair that injury.
Keywords: COVID-19 infection; Lung transplantation; interstitial damage; pulmonary fibrosis; pulmonary medicine; thoracic Surgery.
. 2021 Nov 18;40:169.
doi: 10.11604/pamj.2021.40.169.31223. eCollection 2021.
Increasing incidence of lung transplantation in patients with post-COVID-19 pulmonary fibrosis
Rumi Khajotia[SUP] 1 [/SUP]
Affiliations
- PMID: 34970411
- PMCID: PMC8683460
- DOI: 10.11604/pamj.2021.40.169.31223
Abstract
Twenty months into the COVID-19 pandemic, we are still learning about the various long-term consequences of COVID-19 infection. While many patients do recover with minimal long-term consequences, some patients develop irreversible parenchymal and interstitial lung damage leading to diffuse pulmonary fibrosis. Unfortunately, these are some of the consequences of post-SARS-CoV-2 infection which thousands more people around the world will experience and which will outlast the pandemic for a long time to come. It is now being observed at various leading medical centres around the world that lung transplantation may be the only meaningful treatment available to a select group of patients experiencing serious lung damage and non-resolving COVID-19-associated respiratory failure, resulting from the triad of coronavirus infection, a hyper-inflammatory immune response to it and the inability of the human body to repair that injury.
Keywords: COVID-19 infection; Lung transplantation; interstitial damage; pulmonary fibrosis; pulmonary medicine; thoracic Surgery.