Pandemic H1N1 influenza A viral infection complicated by atypical hemolytic uremic syndrome and diffuse alveolar hemorrhage

[tetano]

Clin Exp Nephrol. 2011 Aug 10. [Epub ahead of print]
Pandemic H1N1 influenza A viral infection complicated by atypical hemolytic uremic syndrome and diffuse alveolar hemorrhage.
Rhee H, Song SH, Lee YJ, Choi HJ, Ahn JH, Seong EY, Lee SB, Kwak IS.
Source

Division of Nephrology, Department of Internal Medicine, Pusan National University Hospital, Gudeok-ro 305, Seo-gu, Busan, 602-739, Republic of Korea.
Abstract

We report here on a case of a 27-year-old man with atypical hemolytic uremic syndrome and diffuse alveolar hemorrhage associated with influenza A H1N1 infection. Treatment with oseltamivir, plasma exchange and hemodiafiltration for the hemolytic uremic syndrome and meticulous supportive care with steroid pulse therapy for the pulmonary alveolar hemorrhage was successful in this case. We discuss the relationship between hemolytic uremic syndrome and influenza A and the underlying immunologic factors that should be tested in a patient with atypical hemolytic uremic syndrome. We also discuss using steroid therapy for patients with H1N1-related diffuse alveolar hemorrhage.

PMID:
21826588
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/21826588