tetano
Editor, Senior Moderator
AIDS. 2010 Aug 26. [Epub ahead of print]
Pandemic influenza A (H1N1) in HIV-1-infected patients.
Perez CM, Dominguez MI, Ceballos ME, Moreno C, Labarca JA, Rabagliati R, Vasquez P, Lasso M, Serri M.
aDepartment of Medicine, School of Medicine, Pontificia Universidad Cat?lica de Chile, Chile bDepartment of Medicine, Hospital San Juan de Dios y Cl?nica D?vila, Chile cDepartment of Medicine, Hospital S?tero del R?o, Chile dDepartment of Medicine, Hospital FACH, Santiago, Chile.
Abstract
OBJECTIVE: To characterize the clinical presentation, course and mortality of pandemic influenza in HIV-1-infected patients in Santiago, Chile.
METHODS: Prospective observational study.
RESULTS: Thirty patients were included (three hospitalized), 93% were on HAART, mean CD4 cell count was 423 cells/mul and viral load was undetectable in 77% of patients. All patients had fever, 90% had cough, 80% had myalgias, 70% had pharyngeal congestion, 47% had coryza, 47% had odynophagia, 37% had headache and 23% had vomiting. Four patients developed pneumonia. All patients received antiviral therapy and no patient died.
CONCLUSIONS: HIV patients infected by the new influenza A pandemic (H1N1) virus behave similarly to the general population.
PMID: 20802295 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20802295
Pandemic influenza A (H1N1) in HIV-1-infected patients.
Perez CM, Dominguez MI, Ceballos ME, Moreno C, Labarca JA, Rabagliati R, Vasquez P, Lasso M, Serri M.
aDepartment of Medicine, School of Medicine, Pontificia Universidad Cat?lica de Chile, Chile bDepartment of Medicine, Hospital San Juan de Dios y Cl?nica D?vila, Chile cDepartment of Medicine, Hospital S?tero del R?o, Chile dDepartment of Medicine, Hospital FACH, Santiago, Chile.
Abstract
OBJECTIVE: To characterize the clinical presentation, course and mortality of pandemic influenza in HIV-1-infected patients in Santiago, Chile.
METHODS: Prospective observational study.
RESULTS: Thirty patients were included (three hospitalized), 93% were on HAART, mean CD4 cell count was 423 cells/mul and viral load was undetectable in 77% of patients. All patients had fever, 90% had cough, 80% had myalgias, 70% had pharyngeal congestion, 47% had coryza, 47% had odynophagia, 37% had headache and 23% had vomiting. Four patients developed pneumonia. All patients received antiviral therapy and no patient died.
CONCLUSIONS: HIV patients infected by the new influenza A pandemic (H1N1) virus behave similarly to the general population.
PMID: 20802295 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20802295