tetano
Editor, Senior Moderator
Pediatr Infect Dis J
. 2022 Jan 27.
doi: 10.1097/INF.0000000000003476. Online ahead of print.
Fatal SARS-CoV-2-Associated Panton-Valentine Leukocidin-producing Staphylococcal Bacteremia: A Nationwide Multicenter Cohort Study
Ulrikka Nygaard[SUP] 1 [/SUP], Andreas Petersen, Anders Rhod Larsen, Maren Johanne Heilskov Rytter, Ulla Hartling, Nikolai Kirkby, Rikke Nymark Hansen, Allan Bybeck Nielsen, Kaare Lundstrøm, Mette Holm, Nadja Hawwa Vissing
Affiliations
Abstract
We reviewed all cases of Panton-Valentine leukocidin-producing Staphylococcus aureus (PVL-SA) bacteremia in Danish children between 2016 and 2021. We found 2 fatal cases with preceding viral prodrome due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Given the usual benign course of SARS-CoV-2 infection in children, awareness of possible superinfection with PVL-SA in a child with rapid deterioration is crucial to ensure adequate treatment, including antimicrobial drugs with antitoxin effect.
. 2022 Jan 27.
doi: 10.1097/INF.0000000000003476. Online ahead of print.
Fatal SARS-CoV-2-Associated Panton-Valentine Leukocidin-producing Staphylococcal Bacteremia: A Nationwide Multicenter Cohort Study
Ulrikka Nygaard[SUP] 1 [/SUP], Andreas Petersen, Anders Rhod Larsen, Maren Johanne Heilskov Rytter, Ulla Hartling, Nikolai Kirkby, Rikke Nymark Hansen, Allan Bybeck Nielsen, Kaare Lundstrøm, Mette Holm, Nadja Hawwa Vissing
Affiliations
- PMID: 35093994
- DOI: 10.1097/INF.0000000000003476
Abstract
We reviewed all cases of Panton-Valentine leukocidin-producing Staphylococcus aureus (PVL-SA) bacteremia in Danish children between 2016 and 2021. We found 2 fatal cases with preceding viral prodrome due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Given the usual benign course of SARS-CoV-2 infection in children, awareness of possible superinfection with PVL-SA in a child with rapid deterioration is crucial to ensure adequate treatment, including antimicrobial drugs with antitoxin effect.