tetano
Editor, Senior Moderator
Pediatr Infect Dis J
. 2022 Apr 21.
doi: 10.1097/INF.0000000000003515. Online ahead of print.
Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy
Thomas Eichholz[SUP] 1 [/SUP], Anne-Marie Arendt[SUP] 1 [/SUP], Ursula Holzer[SUP] 1 [/SUP], Christian Seitz[SUP] 1 [/SUP], Armin Rabsteyn[SUP] 1 [/SUP], Tina Ganzenmueller[SUP] 2 [/SUP], Reinhild Klein[SUP] 3 [/SUP], Juliane Walz[SUP] 4 5 6 7 [/SUP], Peter Lang[SUP] 1 [/SUP]
Affiliations
Abstract
Immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients with malignant disease may be affected by tumor therapy. Here, we report the case of a child with rhabdomyosarcoma and recurrent SARS-CoV-2 infection. Immunologic responses, analyzed by T-cell activity and anti-viral IgG levels, were impaired and not durable as a result of intensive radiochemotherapy.
. 2022 Apr 21.
doi: 10.1097/INF.0000000000003515. Online ahead of print.
Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy
Thomas Eichholz[SUP] 1 [/SUP], Anne-Marie Arendt[SUP] 1 [/SUP], Ursula Holzer[SUP] 1 [/SUP], Christian Seitz[SUP] 1 [/SUP], Armin Rabsteyn[SUP] 1 [/SUP], Tina Ganzenmueller[SUP] 2 [/SUP], Reinhild Klein[SUP] 3 [/SUP], Juliane Walz[SUP] 4 5 6 7 [/SUP], Peter Lang[SUP] 1 [/SUP]
Affiliations
- PMID: 35446806
- DOI: 10.1097/INF.0000000000003515
Abstract
Immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients with malignant disease may be affected by tumor therapy. Here, we report the case of a child with rhabdomyosarcoma and recurrent SARS-CoV-2 infection. Immunologic responses, analyzed by T-cell activity and anti-viral IgG levels, were impaired and not durable as a result of intensive radiochemotherapy.