tetano
Editor, Senior Moderator
Pediatr Radiol
. 2022 May 26.
doi: 10.1007/s00247-022-05393-9. Online ahead of print.
Imaging findings in acute pediatric coronavirus disease 2019 (COVID-19) pneumonia and multisystem inflammatory syndrome in children (MIS-C)
Jessica Kurian[SUP] 1 [/SUP], Einat Blumfield[SUP] 2 [/SUP], Terry L Levin[SUP] 2 [/SUP], Mark C Liszewski[SUP] 2 [/SUP]
Affiliations
Abstract
The two primary manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children are acute coronavirus disease 2019 (COVID-19) pneumonia and multisystem inflammatory syndrome (MIS-C). While most pediatric cases of acute COVID-19 disease are mild or asymptomatic, some children are at risk for developing severe pneumonia. In MIS-C, children present a few weeks after SARS-CoV-2 exposure with a febrile illness that can rapidly progress to shock and multiorgan dysfunction. In both diseases, the clinical and laboratory findings can be nonspecific and present a diagnostic challenge. Thoracic imaging is commonly obtained to assist with initial workup, assessment of disease progression, and guidance of therapy. This paper reviews the radiologic findings of acute COVID-19 pneumonia and MIS-C, highlights the key distinctions between the entities, and summarizes our understanding of the role of imaging in managing SARS-CoV-2-related illness in children.
Keywords: Chest; Children; Computed tomography; Coronavirus disease 2019; Lungs; Multisystem inflammatory syndrome in children; Radiography.
. 2022 May 26.
doi: 10.1007/s00247-022-05393-9. Online ahead of print.
Imaging findings in acute pediatric coronavirus disease 2019 (COVID-19) pneumonia and multisystem inflammatory syndrome in children (MIS-C)
Jessica Kurian[SUP] 1 [/SUP], Einat Blumfield[SUP] 2 [/SUP], Terry L Levin[SUP] 2 [/SUP], Mark C Liszewski[SUP] 2 [/SUP]
Affiliations
- PMID: 35616701
- DOI: 10.1007/s00247-022-05393-9
Abstract
The two primary manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children are acute coronavirus disease 2019 (COVID-19) pneumonia and multisystem inflammatory syndrome (MIS-C). While most pediatric cases of acute COVID-19 disease are mild or asymptomatic, some children are at risk for developing severe pneumonia. In MIS-C, children present a few weeks after SARS-CoV-2 exposure with a febrile illness that can rapidly progress to shock and multiorgan dysfunction. In both diseases, the clinical and laboratory findings can be nonspecific and present a diagnostic challenge. Thoracic imaging is commonly obtained to assist with initial workup, assessment of disease progression, and guidance of therapy. This paper reviews the radiologic findings of acute COVID-19 pneumonia and MIS-C, highlights the key distinctions between the entities, and summarizes our understanding of the role of imaging in managing SARS-CoV-2-related illness in children.
Keywords: Chest; Children; Computed tomography; Coronavirus disease 2019; Lungs; Multisystem inflammatory syndrome in children; Radiography.