tetano
Editor, Senior Moderator
PeerJ
. 2024 Dec 11:12:e18705.
doi: 10.7717/peerj.18705. eCollection 2024. Characterization and clinical outcomes of outpatients with subacute or chronic post COVID-19 cough: a real-world study
Chun Yao[SUP] 1 [/SUP], Dongliang Cheng[SUP] 1 [/SUP], Wenhong Yang[SUP] 1 [/SUP], Yun Guo[SUP] 1 [/SUP], Tong Zhou[SUP] 1 [/SUP]
Affiliations
Background: Limited research exists on the features and management of post-COVID cough. This real-world study investigates outpatients with subacute or chronic post-COVID cough, aiming to delineate characteristics and regimen responses within the population.
Method: We enrolled eligible patients from our outpatient unit between August 2023 and February 2024. Comprehensive clinical data, prescriptions, and patient-reported cough severity were collected during the primary visit and subsequent follow-ups.
Result: A total of 141 patients, aged: 42 ± 14 years old, were included, with 70% being female. The median cough duration was 8 weeks (interquartile range 4-12 weeks). Sixty percent presented with a dry cough, while the rest had coughs with phlegm. Over half reported abnormal laryngeal sensations (54%). Twenty-one percent coughed during the day, while 32% coughed constantly, and 48% experienced nocturnal episodes. Compound methoxyphenamine capsules were the most prescribed, but our study found ICS/LABA to be the most effective, followed by compound methoxyphenamine capsules, montelukast, and Chinese patent drugs.
Conclusion: Females exhibit a higher prevalence of post-COVID cough, and our study recommends ICS/LABA as the preferred treatment. These findings warrant validation through larger, prospectively designed studies.
Keywords: COVID-19; Cough; Outpatients; Real-world study; Regimens.
. 2024 Dec 11:12:e18705.
doi: 10.7717/peerj.18705. eCollection 2024. Characterization and clinical outcomes of outpatients with subacute or chronic post COVID-19 cough: a real-world study
Chun Yao[SUP] 1 [/SUP], Dongliang Cheng[SUP] 1 [/SUP], Wenhong Yang[SUP] 1 [/SUP], Yun Guo[SUP] 1 [/SUP], Tong Zhou[SUP] 1 [/SUP]
Affiliations
- PMID: 39677958
- PMCID: PMC11645979
- DOI: 10.7717/peerj.18705
Background: Limited research exists on the features and management of post-COVID cough. This real-world study investigates outpatients with subacute or chronic post-COVID cough, aiming to delineate characteristics and regimen responses within the population.
Method: We enrolled eligible patients from our outpatient unit between August 2023 and February 2024. Comprehensive clinical data, prescriptions, and patient-reported cough severity were collected during the primary visit and subsequent follow-ups.
Result: A total of 141 patients, aged: 42 ± 14 years old, were included, with 70% being female. The median cough duration was 8 weeks (interquartile range 4-12 weeks). Sixty percent presented with a dry cough, while the rest had coughs with phlegm. Over half reported abnormal laryngeal sensations (54%). Twenty-one percent coughed during the day, while 32% coughed constantly, and 48% experienced nocturnal episodes. Compound methoxyphenamine capsules were the most prescribed, but our study found ICS/LABA to be the most effective, followed by compound methoxyphenamine capsules, montelukast, and Chinese patent drugs.
Conclusion: Females exhibit a higher prevalence of post-COVID cough, and our study recommends ICS/LABA as the preferred treatment. These findings warrant validation through larger, prospectively designed studies.
Keywords: COVID-19; Cough; Outpatients; Real-world study; Regimens.