Tonka
Well-known member
http://hypescience.com/pessoas-naturalmente-resistentes-a-gripe-sao-esperanca-para-vacina-universal/
Portuguese-English translation
People who are naturally resistant to flu help with universal vaccine
According to new research, some people have a natural resistance to all strains of flu.
In 41 healthy volunteers infected with different strains, scientists discovered that people with higher levels of a specific type of white blood cell were less likely to develop severe illness.
This was the first study that could "map" immune individuals, infecting them and then keeping them in quarantine under sterile conditions.
The British researchers believe this discovery will enable them to create a universal vaccine.
They hope to emulate the natural resistance of some of the volunteers through the creation of a vaccine that boosts levels of a specific subset of 'T-cells. "
These cells are able to identify proteins, called peptides, found in virtually all known influenza viruses.
If researchers can increase the population of T cells in people through a vaccine, which is perfectly feasible, it could actually protect them against all strains of flu.
This is not the first time that scientists try to create a universal vaccine against influenza. Several institutions around the world are trying to develop it because of the growing threat of the H5N1 strain of bird flu could mutate and begin spreading from human to human.
However, most research seeks to identify antibodies that bind to sites relatively unchanged from viruses, rather than focusing on the cellular response of the organism.
That is, the current vaccines only work for a few seasons, because they stimulate antibodies that bind to sites of the viruses that mutate rapidly. The new research is more likely to create a successful vaccine. [ Telegraph ]
Portuguese-English translation
People who are naturally resistant to flu help with universal vaccine
According to new research, some people have a natural resistance to all strains of flu.
In 41 healthy volunteers infected with different strains, scientists discovered that people with higher levels of a specific type of white blood cell were less likely to develop severe illness.
This was the first study that could "map" immune individuals, infecting them and then keeping them in quarantine under sterile conditions.
The British researchers believe this discovery will enable them to create a universal vaccine.
They hope to emulate the natural resistance of some of the volunteers through the creation of a vaccine that boosts levels of a specific subset of 'T-cells. "
These cells are able to identify proteins, called peptides, found in virtually all known influenza viruses.
If researchers can increase the population of T cells in people through a vaccine, which is perfectly feasible, it could actually protect them against all strains of flu.
This is not the first time that scientists try to create a universal vaccine against influenza. Several institutions around the world are trying to develop it because of the growing threat of the H5N1 strain of bird flu could mutate and begin spreading from human to human.
However, most research seeks to identify antibodies that bind to sites relatively unchanged from viruses, rather than focusing on the cellular response of the organism.
That is, the current vaccines only work for a few seasons, because they stimulate antibodies that bind to sites of the viruses that mutate rapidly. The new research is more likely to create a successful vaccine. [ Telegraph ]