Mary Wilson
Well-known member
Posted July 19, 2022.
doi: https://doi.org/10.1101/2022.07.19.500662
Sarah Anne Hamer, Chase M Nunez, Christopher Roundy, Wendy Tang, Logan F Thomas, Jack J Richison III, Jamie Benn, Lisa Auckland, Terry Hensley, Walter E Cook, Alex Pauvolid-Correa, Gabriel Hamer
Abstract
After identifying a captive herd of white-tailed deer (WTD) in central Texas with >94% seroprevalence with SARS-CoV-2 neutralizing antibodies in September 2021, we worked retrospectively through archived serum samples of 21 deer and detected seroconversion of all animals between December 2020 and January 2021. We then collected prospective samples to conclude that the duration of persistence of neutralizing antibodies is at least 13 months for 19 (90.5%) of the animals, with two animals converting to seronegative after six and eight months. Antibody titers generally waned over this time frame, but three deer had a temporary 4 to 8-fold increases in PRNT titers over a month after seroconversion; anamnestic response cannot be ruled out.
https://www.biorxiv.org/content/10.1101/2022.07.19.500662v1.full.pdf
doi: https://doi.org/10.1101/2022.07.19.500662
Sarah Anne Hamer, Chase M Nunez, Christopher Roundy, Wendy Tang, Logan F Thomas, Jack J Richison III, Jamie Benn, Lisa Auckland, Terry Hensley, Walter E Cook, Alex Pauvolid-Correa, Gabriel Hamer
Abstract
After identifying a captive herd of white-tailed deer (WTD) in central Texas with >94% seroprevalence with SARS-CoV-2 neutralizing antibodies in September 2021, we worked retrospectively through archived serum samples of 21 deer and detected seroconversion of all animals between December 2020 and January 2021. We then collected prospective samples to conclude that the duration of persistence of neutralizing antibodies is at least 13 months for 19 (90.5%) of the animals, with two animals converting to seronegative after six and eight months. Antibody titers generally waned over this time frame, but three deer had a temporary 4 to 8-fold increases in PRNT titers over a month after seroconversion; anamnestic response cannot be ruled out.
https://www.biorxiv.org/content/10.1101/2022.07.19.500662v1.full.pdf
