tetano
Editor, Senior Moderator
Open Virol J. 2011;5:22-6. Epub 2011 Apr 7.
Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection.
Ciccozzi M, Babakir-Mina M, Lo Presti A, Marcuccilli F, Perno CF, Ciotti M.
Source
Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita', Rome, Italy.
Abstract
During the spring of 2009, a new influenza A (H1N1) virus of swine origin emerged and spread worldwide causing a pandemic influenza. Here, 329 naso-pharyngeal swabs collected from patients with flu-like symptoms were analyzed by real-time PCR for the presence of H1N1 2009 pandemic virus. Twenty-five samples collected from immunocompetent and immunodepressed patients contained the H1N1 pandemic virus. Phylogenetic analysis of the hemagglutinin and neuraminidase genes showed no obvious differences in terms of similarity and/or homology between the sequences identified in immunocompetent individuals and those obtained from immunocompromised patients. Pre-existing clinical conditions may influence the outcome of H1N1 disease.
PMID:
21660186
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/21660186
Phylogenesis and Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection.
Ciccozzi M, Babakir-Mina M, Lo Presti A, Marcuccilli F, Perno CF, Ciotti M.
Source
Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita', Rome, Italy.
Abstract
During the spring of 2009, a new influenza A (H1N1) virus of swine origin emerged and spread worldwide causing a pandemic influenza. Here, 329 naso-pharyngeal swabs collected from patients with flu-like symptoms were analyzed by real-time PCR for the presence of H1N1 2009 pandemic virus. Twenty-five samples collected from immunocompetent and immunodepressed patients contained the H1N1 pandemic virus. Phylogenetic analysis of the hemagglutinin and neuraminidase genes showed no obvious differences in terms of similarity and/or homology between the sequences identified in immunocompetent individuals and those obtained from immunocompromised patients. Pre-existing clinical conditions may influence the outcome of H1N1 disease.
PMID:
21660186
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/21660186