tetano
Editor, Senior Moderator
PLoS One
. 2021 Jul 15;16(7):e0254012.
doi: 10.1371/journal.pone.0254012. eCollection 2021.
Early centralized isolation strategy for all confirmed cases of COVID-19 remains a core intervention to disrupt the pandemic spreading significantly
Nguyen Hai Nam[SUP] 1 2 3 [/SUP], Phan Thi My Tien[SUP] 3 4 [/SUP], Le Van Truong[SUP] 3 5 [/SUP], Toka Aziz El-Ramly[SUP] 3 6 [/SUP], Pham Gia Anh[SUP] 3 4 [/SUP], Nguyen Thi Hien[SUP] 3 7 [/SUP], El Marabea Mahmoud[SUP] 3 8 [/SUP], Mennatullah Mohamed Eltaras[SUP] 3 9 [/SUP], Sarah Abd Elaziz Khader[SUP] 3 10 [/SUP], Mohammed Salah Desokey[SUP] 3 11 [/SUP], Ramy Magdy Gayed[SUP] 3 12 [/SUP], Shamael Thabit Mohammed Alhady[SUP] 3 13 [/SUP], Bao-Tran Do Le[SUP] 3 14 [/SUP], Do Phuc Nhu Nguyen[SUP] 3 15 [/SUP], Ranjit Tiwari[SUP] 3 16 [/SUP], Mohammed Eldoadoa[SUP] 3 17 [/SUP], Britney Howard[SUP] 3 18 [/SUP], Tran Thanh Trung[SUP] 3 [/SUP], Nguyen Tien Huy[SUP] 19 [/SUP]
Affiliations
Abstract
Background: In response to the spread of the coronavirus disease 2019 (COVID-19), plenty of control measures were proposed. To assess the impact of current control measures on the number of new case indices 14 countries with the highest confirmed cases, highest mortality rate, and having a close relationship with the outbreak's origin; were selected and analyzed.
Methods: In the study, we analyzed the impact of five control measures, including centralized isolation of all confirmed cases, closure of schools, closure of public areas, closure of cities, and closure of borders of the 14 targeted countries according to their timing; by comparing its absolute effect average, its absolute effect cumulative, and its relative effect average.
Results: Our analysis determined that early centralized isolation of all confirmed cases was represented as a core intervention in significantly disrupting the pandemic's spread. This strategy helped in successfully controlling the early stage of the outbreak when the total number of cases were under 100, without the requirement of the closure of cities and public areas, which would impose a negative impact on the society and its economy. However, when the number of cases increased with the apparition of new clusters, coordination between centralized isolation and non-pharmaceutical interventions facilitated control of the crisis efficiently.
Conclusion: Early centralized isolation of all confirmed cases should be implemented at the time of the first detected infectious case.
. 2021 Jul 15;16(7):e0254012.
doi: 10.1371/journal.pone.0254012. eCollection 2021.
Early centralized isolation strategy for all confirmed cases of COVID-19 remains a core intervention to disrupt the pandemic spreading significantly
Nguyen Hai Nam[SUP] 1 2 3 [/SUP], Phan Thi My Tien[SUP] 3 4 [/SUP], Le Van Truong[SUP] 3 5 [/SUP], Toka Aziz El-Ramly[SUP] 3 6 [/SUP], Pham Gia Anh[SUP] 3 4 [/SUP], Nguyen Thi Hien[SUP] 3 7 [/SUP], El Marabea Mahmoud[SUP] 3 8 [/SUP], Mennatullah Mohamed Eltaras[SUP] 3 9 [/SUP], Sarah Abd Elaziz Khader[SUP] 3 10 [/SUP], Mohammed Salah Desokey[SUP] 3 11 [/SUP], Ramy Magdy Gayed[SUP] 3 12 [/SUP], Shamael Thabit Mohammed Alhady[SUP] 3 13 [/SUP], Bao-Tran Do Le[SUP] 3 14 [/SUP], Do Phuc Nhu Nguyen[SUP] 3 15 [/SUP], Ranjit Tiwari[SUP] 3 16 [/SUP], Mohammed Eldoadoa[SUP] 3 17 [/SUP], Britney Howard[SUP] 3 18 [/SUP], Tran Thanh Trung[SUP] 3 [/SUP], Nguyen Tien Huy[SUP] 19 [/SUP]
Affiliations
- PMID: 34264966
- DOI: 10.1371/journal.pone.0254012
Abstract
Background: In response to the spread of the coronavirus disease 2019 (COVID-19), plenty of control measures were proposed. To assess the impact of current control measures on the number of new case indices 14 countries with the highest confirmed cases, highest mortality rate, and having a close relationship with the outbreak's origin; were selected and analyzed.
Methods: In the study, we analyzed the impact of five control measures, including centralized isolation of all confirmed cases, closure of schools, closure of public areas, closure of cities, and closure of borders of the 14 targeted countries according to their timing; by comparing its absolute effect average, its absolute effect cumulative, and its relative effect average.
Results: Our analysis determined that early centralized isolation of all confirmed cases was represented as a core intervention in significantly disrupting the pandemic's spread. This strategy helped in successfully controlling the early stage of the outbreak when the total number of cases were under 100, without the requirement of the closure of cities and public areas, which would impose a negative impact on the society and its economy. However, when the number of cases increased with the apparition of new clusters, coordination between centralized isolation and non-pharmaceutical interventions facilitated control of the crisis efficiently.
Conclusion: Early centralized isolation of all confirmed cases should be implemented at the time of the first detected infectious case.