Giuseppe
Emeritus
[Source: PLoS ONE, full text: (LINK). Abstract, edited.]
------
Research Article
European H16N3 Gull Influenza Virus Attaches to the Human Respiratory Tract and Eye
Cecilia Lindskog, Patrik Ellstr?m, Bj?rn Olsen, Fredrik Pont?n, Debby van Riel, Vincent J. Munster, Daniel Gonz?lez-Acu?a, Thijs Kuiken, Elsa Jourdain
Abstract
We explored the attachment of an H16N3 influenza virus to human, mallard, and gull tissues using virus histochemistry applied to tissue microarrays and employing human and mallard viruses as references. Of the viruses tested, the H16N3 gull virus most readily attached to the human respiratory tract and eye. These results underscore the need to assess the potential for gull influenza viruses to replicate in human tissues and further investigate the role of gulls in influenza virus ecology.
Citation: Lindskog C, Ellstr?m P, Olsen B, Pont?n F, van Riel D, et al. (2013) European H16N3 Gull Influenza Virus Attaches to the Human Respiratory Tract and Eye. PLoS ONE 8(4): e60757. doi:10.1371/journal.pone.0060757
Editor: Matthias Johannes Schnell, Thomas Jefferson University, United States of America
Received: December 6, 2012; Accepted: March 1, 2013; Published: April 8, 2013
This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.
Funding: This study was financially supported by the Swedish Research Council for Spatial Planning and Agriculture (FORMAS 216-2009-1220), the Swedish Research Council Vetenskapsr?det (VR 2010-36963-78952-78), the Knut and Alice Wallenberg Foundation, and the FONDECYT project (1070464). VJM is supported by the Division of Intramural Research, the National Institute of Allergy and Infectious Diseases, and the National Institutes of Health. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests: The authors have declared that no competing interests exist.
-European H16N3 Gull Influenza Virus Attaches to the Human Respiratory Tract and Eye
Cecilia Lindskog, Patrik Ellstr?m, Bj?rn Olsen, Fredrik Pont?n, Debby van Riel, Vincent J. Munster, Daniel Gonz?lez-Acu?a, Thijs Kuiken, Elsa Jourdain
Abstract
We explored the attachment of an H16N3 influenza virus to human, mallard, and gull tissues using virus histochemistry applied to tissue microarrays and employing human and mallard viruses as references. Of the viruses tested, the H16N3 gull virus most readily attached to the human respiratory tract and eye. These results underscore the need to assess the potential for gull influenza viruses to replicate in human tissues and further investigate the role of gulls in influenza virus ecology.
Citation: Lindskog C, Ellstr?m P, Olsen B, Pont?n F, van Riel D, et al. (2013) European H16N3 Gull Influenza Virus Attaches to the Human Respiratory Tract and Eye. PLoS ONE 8(4): e60757. doi:10.1371/journal.pone.0060757
Editor: Matthias Johannes Schnell, Thomas Jefferson University, United States of America
Received: December 6, 2012; Accepted: March 1, 2013; Published: April 8, 2013
This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.
Funding: This study was financially supported by the Swedish Research Council for Spatial Planning and Agriculture (FORMAS 216-2009-1220), the Swedish Research Council Vetenskapsr?det (VR 2010-36963-78952-78), the Knut and Alice Wallenberg Foundation, and the FONDECYT project (1070464). VJM is supported by the Division of Intramural Research, the National Institute of Allergy and Infectious Diseases, and the National Institutes of Health. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests: The authors have declared that no competing interests exist.
------