tetano
Editor, Senior Moderator
PLoS One
. 2024 Jan 12;19(1):e0296700.
doi: 10.1371/journal.pone.0296700. eCollection 2024. The incidence, characteristics, impact and risk factors of post-COVID chronic pain in Thailand: A single-center cross-sectional study
Suratsawadee Wangnamthip[SUP] 1 [/SUP], Nantthasorn Zinboonyahgoon[SUP] 1 [/SUP], Pranee Rushatamukayanunt[SUP] 1 [/SUP], Patcha Papaisarn[SUP] 1 [/SUP], Burapa Pajina[SUP] 1 [/SUP], Thanawut Jitsinthunun[SUP] 1 [/SUP], Panuwat Promsin[SUP] 2 [/SUP], Rujipas Sirijatuphat[SUP] 2 [/SUP], César Fernández-de-Las-Peñas[SUP] 3 4 [/SUP], Lars Arendt-Nielsen[SUP] 3 5 6 [/SUP], Daniel Ciampi de Andrade[SUP] 3 [/SUP]
Affiliations
The COVID-19 pandemic has affected millions of individuals worldwide. Pain has emerged as a significant post-COVID-19 symptom. This study investigated the incidence, characteristics, and risk factors of post-COVID chronic pain (PCCP) in Thailand. A cross-sectional study was conducted in participants who had been infected, including those hospitalized and monitored at home by SARS-CoV-2 from August to September 2021. Data were collected for screening from medical records, and phone interviews were done between 3 to 6 months post-infection. Participants were classified into 1) no-pain, 2) PCCP, 3) chronic pain that has been aggravated by COVID-19, or 4) chronic pain that has not been aggravated by COVID-19. Pain interference and quality of life were evaluated with the Brief Pain Inventory and EuroQol Five Dimensions Five Levels Questionnaire. From 1,019 participants, 90% of the participants had mild infection, assessed by WHO progression scale. The overall incidence of PCCP was 3.2% (95% CI 2.3-4.5), with 2.8% (95% CI 2.0-4.1) in mild infection, 5.2% (95% CI 1.2-14.1) in moderate infection and 8.5% (95% CI 3.4-19.9) in severe infection. Most participants (83.3%) reported pain in the back and lower extremities and were classified as musculoskeletal pain and headache (8.3%). Risk factors associated with PCCP, included female sex (relative risk [RR] 2.2, 95% CI 1.0-4.9) and greater COVID-19 severity (RR 3.5, 95% CI 1.1-11.7). Participants with COVID-19-related exacerbated chronic pain displayed higher pain interferences and lower utility scores than other groups. In conclusion, this study highlights the incidence, features, and risk factors of post-COVID chronic pain (PCCP) in Thailand. It emphasizes the need to monitor and address PCCP, especially in severe cases, among females, and individuals with a history of chronic pain to improve their quality of life in the context of the ongoing COVID-19 pandemic.
. 2024 Jan 12;19(1):e0296700.
doi: 10.1371/journal.pone.0296700. eCollection 2024. The incidence, characteristics, impact and risk factors of post-COVID chronic pain in Thailand: A single-center cross-sectional study
Suratsawadee Wangnamthip[SUP] 1 [/SUP], Nantthasorn Zinboonyahgoon[SUP] 1 [/SUP], Pranee Rushatamukayanunt[SUP] 1 [/SUP], Patcha Papaisarn[SUP] 1 [/SUP], Burapa Pajina[SUP] 1 [/SUP], Thanawut Jitsinthunun[SUP] 1 [/SUP], Panuwat Promsin[SUP] 2 [/SUP], Rujipas Sirijatuphat[SUP] 2 [/SUP], César Fernández-de-Las-Peñas[SUP] 3 4 [/SUP], Lars Arendt-Nielsen[SUP] 3 5 6 [/SUP], Daniel Ciampi de Andrade[SUP] 3 [/SUP]
Affiliations
- PMID: 38215071
- PMCID: PMC10786369
- DOI: 10.1371/journal.pone.0296700
The COVID-19 pandemic has affected millions of individuals worldwide. Pain has emerged as a significant post-COVID-19 symptom. This study investigated the incidence, characteristics, and risk factors of post-COVID chronic pain (PCCP) in Thailand. A cross-sectional study was conducted in participants who had been infected, including those hospitalized and monitored at home by SARS-CoV-2 from August to September 2021. Data were collected for screening from medical records, and phone interviews were done between 3 to 6 months post-infection. Participants were classified into 1) no-pain, 2) PCCP, 3) chronic pain that has been aggravated by COVID-19, or 4) chronic pain that has not been aggravated by COVID-19. Pain interference and quality of life were evaluated with the Brief Pain Inventory and EuroQol Five Dimensions Five Levels Questionnaire. From 1,019 participants, 90% of the participants had mild infection, assessed by WHO progression scale. The overall incidence of PCCP was 3.2% (95% CI 2.3-4.5), with 2.8% (95% CI 2.0-4.1) in mild infection, 5.2% (95% CI 1.2-14.1) in moderate infection and 8.5% (95% CI 3.4-19.9) in severe infection. Most participants (83.3%) reported pain in the back and lower extremities and were classified as musculoskeletal pain and headache (8.3%). Risk factors associated with PCCP, included female sex (relative risk [RR] 2.2, 95% CI 1.0-4.9) and greater COVID-19 severity (RR 3.5, 95% CI 1.1-11.7). Participants with COVID-19-related exacerbated chronic pain displayed higher pain interferences and lower utility scores than other groups. In conclusion, this study highlights the incidence, features, and risk factors of post-COVID chronic pain (PCCP) in Thailand. It emphasizes the need to monitor and address PCCP, especially in severe cases, among females, and individuals with a history of chronic pain to improve their quality of life in the context of the ongoing COVID-19 pandemic.