tetano
Editor, Senior Moderator
PLoS One
. 2023 Nov 28;18(11):e0294427.
doi: 10.1371/journal.pone.0294427. eCollection 2023. Ultraviolet-C light at 222 nm has a high disinfecting spectrum in environments contaminated by infectious pathogens, including SARS-CoV-2
Byeong-Min Song[SUP] 1 [/SUP], Gun-Hee Lee[SUP] 1 [/SUP], Hee-Jeong Han[SUP] 1 [/SUP], Ju-Hee Yang[SUP] 1 [/SUP], Eun-Gyeong Lee[SUP] 1 [/SUP], Hyunji Gu[SUP] 1 [/SUP], Ha-Kyeong Park[SUP] 1 [/SUP], Kyunga Ryu[SUP] 2 [/SUP], Jinwoo Kim[SUP] 2 [/SUP], Sang-Min Kang[SUP] 1 [/SUP], Dongseob Tark[SUP] 1 [/SUP]
Affiliations
Ultraviolet light (UV) acts as a powerful disinfectant and can prevent contamination of personal hygiene from various contaminated environments. The 222-nm wavelength of UV-C has a highly effective sterilization activity and is safer than 275-nm UV-C. We investigated the irradiation efficacy of 222-nm UV-C against contaminating bacteria and viruses in liquid and fabric environments. We conducted colony-forming unit assays to determine the number of viable cells and a 50% tissue culture infectious dose assay to evaluate the virus titration. A minimum dose of 27 mJ/cm2 of 222-nm UV-C was required for >95% germicidal activity for gram-negative and -positive bacteria. A 25.1 mJ/cm2 dose could ensure >95% virucidal activity against low-pathogenic avian influenza virus and severe acute respiratory syndrome coronavirus (SARS-CoV-2). In addition, this energy dose of 222-nm UV-C effectively inactivated SARS-CoV-2 variants, Delta and Omicron. These results provide valuable information on the disinfection efficiency of 222-nm UV-C in bacterial and virus-contaminated environments and can also develop into a powerful tool for individual hygiene.
. 2023 Nov 28;18(11):e0294427.
doi: 10.1371/journal.pone.0294427. eCollection 2023. Ultraviolet-C light at 222 nm has a high disinfecting spectrum in environments contaminated by infectious pathogens, including SARS-CoV-2
Byeong-Min Song[SUP] 1 [/SUP], Gun-Hee Lee[SUP] 1 [/SUP], Hee-Jeong Han[SUP] 1 [/SUP], Ju-Hee Yang[SUP] 1 [/SUP], Eun-Gyeong Lee[SUP] 1 [/SUP], Hyunji Gu[SUP] 1 [/SUP], Ha-Kyeong Park[SUP] 1 [/SUP], Kyunga Ryu[SUP] 2 [/SUP], Jinwoo Kim[SUP] 2 [/SUP], Sang-Min Kang[SUP] 1 [/SUP], Dongseob Tark[SUP] 1 [/SUP]
Affiliations
- PMID: 38015931
- DOI: 10.1371/journal.pone.0294427
Ultraviolet light (UV) acts as a powerful disinfectant and can prevent contamination of personal hygiene from various contaminated environments. The 222-nm wavelength of UV-C has a highly effective sterilization activity and is safer than 275-nm UV-C. We investigated the irradiation efficacy of 222-nm UV-C against contaminating bacteria and viruses in liquid and fabric environments. We conducted colony-forming unit assays to determine the number of viable cells and a 50% tissue culture infectious dose assay to evaluate the virus titration. A minimum dose of 27 mJ/cm2 of 222-nm UV-C was required for >95% germicidal activity for gram-negative and -positive bacteria. A 25.1 mJ/cm2 dose could ensure >95% virucidal activity against low-pathogenic avian influenza virus and severe acute respiratory syndrome coronavirus (SARS-CoV-2). In addition, this energy dose of 222-nm UV-C effectively inactivated SARS-CoV-2 variants, Delta and Omicron. These results provide valuable information on the disinfection efficiency of 222-nm UV-C in bacterial and virus-contaminated environments and can also develop into a powerful tool for individual hygiene.