Mary Wilson
Well-known member
https://doi.org/10.1164/rccm.202008-3376IM PubMed: 33448891
Matthew F. Mart [SUP]1[/SUP][SUP],[/SUP][SUP]2[/SUP], Stephanie G. Norfolk [SUP]1[/SUP], Lisa N. Flemmons [SUP]1[/SUP], John W. Stokes [SUP]3[/SUP][SUP],[/SUP][SUP]4[/SUP], Matthew D. Bacchetta [SUP]3[/SUP][SUP],[/SUP][SUP]4[/SUP], Anil J. Trindade [SUP]1[/SUP], Jonathan D. Casey [SUP]1[/SUP], Matthew W. Semler [SUP]1[/SUP], E. Wesley Ely [SUP]1[/SUP][SUP],[/SUP][SUP]2[/SUP], and Michael J. Noto [SUP]1[/SUP]
Pneumomediastinum is an uncommon complication of acute respiratory distress syndrome (ARDS) from viral infections, including severe acute respiratory syndrome coronavirus 1 (1). Barotrauma from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (i.e., coronavirus disease [COVID-19]) has been increasingly described (2, 3).
We report five patients with pneumomediastinum of 92 critically ill, mechanically ventilated adults with ARDS from COVID-19 at our institution from March 1, 2020, through August 31, 2020 (Figure 1). Unlike other reports (4, 5), no patient had pneumothorax or required tube thoracostomy at diagnosis, suggesting alveolar rupture occurred without disruption of visceral pleura. Pneumomediastinum developed between 24 hours before and 9 days after initiation of mechanical ventilation without evidence of tracheal injury or the use of recruitment maneuvers.
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https://www.atsjournals.org/doi/full/10.1164/rccm.202008-3376IM
Matthew F. Mart [SUP]1[/SUP][SUP],[/SUP][SUP]2[/SUP], Stephanie G. Norfolk [SUP]1[/SUP], Lisa N. Flemmons [SUP]1[/SUP], John W. Stokes [SUP]3[/SUP][SUP],[/SUP][SUP]4[/SUP], Matthew D. Bacchetta [SUP]3[/SUP][SUP],[/SUP][SUP]4[/SUP], Anil J. Trindade [SUP]1[/SUP], Jonathan D. Casey [SUP]1[/SUP], Matthew W. Semler [SUP]1[/SUP], E. Wesley Ely [SUP]1[/SUP][SUP],[/SUP][SUP]2[/SUP], and Michael J. Noto [SUP]1[/SUP]Pneumomediastinum is an uncommon complication of acute respiratory distress syndrome (ARDS) from viral infections, including severe acute respiratory syndrome coronavirus 1 (1). Barotrauma from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (i.e., coronavirus disease [COVID-19]) has been increasingly described (2, 3).
We report five patients with pneumomediastinum of 92 critically ill, mechanically ventilated adults with ARDS from COVID-19 at our institution from March 1, 2020, through August 31, 2020 (Figure 1). Unlike other reports (4, 5), no patient had pneumothorax or required tube thoracostomy at diagnosis, suggesting alveolar rupture occurred without disruption of visceral pleura. Pneumomediastinum developed between 24 hours before and 9 days after initiation of mechanical ventilation without evidence of tracheal injury or the use of recruitment maneuvers.
...
https://www.atsjournals.org/doi/full/10.1164/rccm.202008-3376IM