tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2016 Jul 6. doi: 10.1111/irv.12405. [Epub ahead of print]
[h=1]Pneumonia and influenza hospitalizations among children under 5 years of age in Suzhou, China, 2005-2011.[/h] Zhang X[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Zhang J[SUP]4[/SUP], Chen L[SUP]4[/SUP], Feng L[SUP]5[/SUP], Yu H[SUP]5[/SUP], Zhao G[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Zhang T[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] The disease burden of influenza among children in China has not been well described.
[h=4]OBJECTIVE:[/h] To estimate the influenza-associated excess hospitalization rate and compare the hospitalization length and costs between pneumonia and influenza (P&I) and other community-acquired diseases (CAD) in Suzhou, China.
[h=4]METHODS:[/h] We retrospectively collected hospital discharge data on pediatric patients' discharge diagnosis, hospital costs and length of hospital stay in Suzhou. P&I hospitalization was defined as a primary discharge diagnosis of pneumonia and influenza disease (ICD-10 codes J09-J18). Other CAD were common community-acquired diseases among children. Negative binomial regression models were used to estimate the weekly P&I hospitalizations in Suzhou. Excess P&I hospitalizations due to influenza were calculated as the difference in P&I hospitalizations between the epidemic period and the baseline period. Baseline was defined as when the influenza positive rates were <5% for two consecutive weeks.
[h=4]RESULTS:[/h] From October 2005 to September 2011, we identified a total of 180,091 all-cause hospitalizations among children <5 years in Suzhou City. The rates of P&I and influenza-associated excess hospitalizations were highest in the 2009-2010 pandemic and 2010-2011 post-pandemic seasons. Infants <6 months had the highest P&I hospitalization rates, the longest hospital stays (7.5-8.0 days) and the highest hospitalization costs for P&I. Compared with other CAD, children admitted for P&I had longer hospital stays and higher hospitalization costs.
[h=4]CONCLUSIONS:[/h] The influenza-associated P&I hospitalization rates and economic burden were high among children. Targeted influenza prevention and control strategies for young children in Suzhou may reduce the influenza-associated hospitalizations in this age group. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
PMID: 27383534 DOI: 10.1111/irv.12405
[PubMed - as supplied by publisher]
[h=1]Pneumonia and influenza hospitalizations among children under 5 years of age in Suzhou, China, 2005-2011.[/h] Zhang X[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Zhang J[SUP]4[/SUP], Chen L[SUP]4[/SUP], Feng L[SUP]5[/SUP], Yu H[SUP]5[/SUP], Zhao G[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Zhang T[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] The disease burden of influenza among children in China has not been well described.
[h=4]OBJECTIVE:[/h] To estimate the influenza-associated excess hospitalization rate and compare the hospitalization length and costs between pneumonia and influenza (P&I) and other community-acquired diseases (CAD) in Suzhou, China.
[h=4]METHODS:[/h] We retrospectively collected hospital discharge data on pediatric patients' discharge diagnosis, hospital costs and length of hospital stay in Suzhou. P&I hospitalization was defined as a primary discharge diagnosis of pneumonia and influenza disease (ICD-10 codes J09-J18). Other CAD were common community-acquired diseases among children. Negative binomial regression models were used to estimate the weekly P&I hospitalizations in Suzhou. Excess P&I hospitalizations due to influenza were calculated as the difference in P&I hospitalizations between the epidemic period and the baseline period. Baseline was defined as when the influenza positive rates were <5% for two consecutive weeks.
[h=4]RESULTS:[/h] From October 2005 to September 2011, we identified a total of 180,091 all-cause hospitalizations among children <5 years in Suzhou City. The rates of P&I and influenza-associated excess hospitalizations were highest in the 2009-2010 pandemic and 2010-2011 post-pandemic seasons. Infants <6 months had the highest P&I hospitalization rates, the longest hospital stays (7.5-8.0 days) and the highest hospitalization costs for P&I. Compared with other CAD, children admitted for P&I had longer hospital stays and higher hospitalization costs.
[h=4]CONCLUSIONS:[/h] The influenza-associated P&I hospitalization rates and economic burden were high among children. Targeted influenza prevention and control strategies for young children in Suzhou may reduce the influenza-associated hospitalizations in this age group. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
PMID: 27383534 DOI: 10.1111/irv.12405
[PubMed - as supplied by publisher]