Polioencephalomalacia in ruminants has recently been associated with high sulfur intake

[Emily]

http://www.merckvetmanual.com/mvm/n...alacia/overview_of_polioencephalomalacia.html

[h=1]Overview of Polioencephalomalacia[/h] [h=2](Cerebrocortical necrosis)[/h] Polioencephalomalacia (PEM) is an important neurologic disease of ruminants that is seen worldwide. Cattle, sheep, goats, deer, and camelids are affected. PEM is a pathologic diagnosis and a common end point of several conditions. Historically, PEM has been associated with altered thiamine status, but more recently an association with high sulfur intake has been seen. Other toxic or metabolic diseases (eg, acute lead poisoning, sodium toxicosis/water deprivation) can result in PEM as well...