tetano
Editor, Senior Moderator
Dev Comp Immunol. 2013 May 21. pii: S0145-305X(13)00138-9. doi: 10.1016/j.dci.2013.05.011. [Epub ahead of print]
Potential directions for chicken immunology research.
Stewart CR, Keyburn AL, Deffrasnes C, Mark Tompkins S.
Source
CSIRO Biosecurity Flagship, Australian Animal Health Laboratory, Geelong, Victoria, 3220 Australia. Electronic address: cameron.stewart@csiro.au.
Abstract
The importance of poultry, particularly chicken, as a food source continues to increase globally. Moreover, zoonotic infectious diseases such as avian influenza virus not only continue to impact poultry production, but also pose an increasing threat to public health. This review discusses the importance of poultry in both agricultural and public health arenas. Recent developments in avian immunology are described, with an emphasis on host-pathogen interactions and noting differences from mammalian systems. Next generation technologies including functional genomics and targeted gene disruption (e.g. zinc finger nucleases and meganucleases) are discussed as new approaches for not only understanding immune responses in poultry, but also as novel disease intervention strategies.
Copyright ? 2013. Published by Elsevier Ltd.
PMID:
23707787
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23707787
Potential directions for chicken immunology research.
Stewart CR, Keyburn AL, Deffrasnes C, Mark Tompkins S.
Source
CSIRO Biosecurity Flagship, Australian Animal Health Laboratory, Geelong, Victoria, 3220 Australia. Electronic address: cameron.stewart@csiro.au.
Abstract
The importance of poultry, particularly chicken, as a food source continues to increase globally. Moreover, zoonotic infectious diseases such as avian influenza virus not only continue to impact poultry production, but also pose an increasing threat to public health. This review discusses the importance of poultry in both agricultural and public health arenas. Recent developments in avian immunology are described, with an emphasis on host-pathogen interactions and noting differences from mammalian systems. Next generation technologies including functional genomics and targeted gene disruption (e.g. zinc finger nucleases and meganucleases) are discussed as new approaches for not only understanding immune responses in poultry, but also as novel disease intervention strategies.
Copyright ? 2013. Published by Elsevier Ltd.
PMID:
23707787
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23707787