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Prog Pediatr Cardiol . Asymmetric septal edema masking as hypertrophy in an infant with COVID-19 myocarditis

tetano

Editor, Senior Moderator
Prog Pediatr Cardiol


. 2021 Nov 22;101464.
doi: 10.1016/j.ppedcard.2021.101464. Online ahead of print.
Asymmetric septal edema masking as hypertrophy in an infant with COVID-19 myocarditis


Jonathan J Edwards[SUP] 1 [/SUP], Matthew A Harris[SUP] 1 2 [/SUP], Amir Toib[SUP] 3 [/SUP], Danielle S Burstein[SUP] 1 [/SUP], Joseph W Rossano[SUP] 1 [/SUP]



Affiliations

Abstract

Cardiac disease in pediatric patients due to coronavirus SARS-CoV-2 disease (COVID-19) include myocarditis and multisystem inflammatory syndrome, both of which can present with a broad range in severity. Here we describe an infant with COVID-19 causing fulminant myocarditis with inotrope-resistant acute heart failure requiring extracorporeal membrane oxygenation. The patient demonstrated an atypical finding of localized septal thickening suggestive of hypertrophic cardiomyopathy, but the diagnosis of myocarditis was confirmed by cardiac MRI. Serial echocardiography illustrated complete resolution of septal hypertrophy and normalized cardiac function. The current report highlights the potential severity of COVID-19 associated myocarditis, the potential for recovery, and the utility of cardiac MRI in confirming the mechanism.

Keywords: BNP, brain natriuretic peptide; COVID-19; COVID-19, coronavirus SARS-CoV-2 disease; ECMO, extracorporeal membrane oxygenation; Extracorporeal membrane oxygenation; ICU, intensive care unit; MIS-C, multisystem inflammatory syndrome; MRI, magnetic resonance imaging; Magnetic resonance imaging; Myocarditis; PCR, polymerase chain reaction.
 
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