tetano
Editor, Senior Moderator
Psychiatry Res
. 2023 Nov 24:331:115625.
doi: 10.1016/j.psychres.2023.115625. Online ahead of print. Long-term impact of the COVID-19 pandemic on obsessive-compulsive disorder
Lavanya P Sharma[SUP] 1 [/SUP], Srinivas Balachander[SUP] 2 [/SUP], Navya Spurthi Thatikonda[SUP] 1 [/SUP], Uma Maheswari Ganesh[SUP] 3 [/SUP], Chethana Kishore[SUP] 1 [/SUP], Mahashweta Bhattacharya[SUP] 3 [/SUP], Abel Thamby[SUP] 4 [/SUP], Jaisoorya Ts[SUP] 1 [/SUP], Janardhanan C Narayanaswamy[SUP] 5 [/SUP], Shyam Sundar Arumugham[SUP] 1 [/SUP], Yc Janardhan Reddy[SUP] 1 [/SUP]
Affiliations
There is limited data on the long-term effect of the COVID-19 pandemic on obsessive-compulsive disorder (OCD). We report on the course of a cohort of individuals with OCD followed-up over a period of one year during the first wave of the COVID-19 pandemic in India. A cohort of 240 individuals registered at a specialty OCD clinic was regularly followed-up using standardized rating tools at three months, six months, and one year into the onset of the COVID-19 pandemic in India. These were compared with clinical ratings recorded in a comparable historical cohort of 207 individuals with OCD, followed up during a non-pandemic year. The pandemic and non-pandemic (historical control) cohorts did not differ in illness severity and rate of relapse. It was found that COVID-19-related anxiety declined over time. Among those patients who were treatment responders prior to the pandemic, COVID-19-related anxiety and non-adherence to medication predicted a relapse of symptoms. Contrary to our expectations, the rate of relapse and illness trajectory in the pandemic cohort did not differ from the non-pandemic cohort, suggesting that the pandemic did not impact our largely medication-adherent cohort. Adherence to treatment seemed to have a protective effect during the pandemic.
Keywords: COVID-19; Coronavirus; Course; OCD; Obsessive-compulsive disorder; Outcome; Pandemic.
. 2023 Nov 24:331:115625.
doi: 10.1016/j.psychres.2023.115625. Online ahead of print. Long-term impact of the COVID-19 pandemic on obsessive-compulsive disorder
Lavanya P Sharma[SUP] 1 [/SUP], Srinivas Balachander[SUP] 2 [/SUP], Navya Spurthi Thatikonda[SUP] 1 [/SUP], Uma Maheswari Ganesh[SUP] 3 [/SUP], Chethana Kishore[SUP] 1 [/SUP], Mahashweta Bhattacharya[SUP] 3 [/SUP], Abel Thamby[SUP] 4 [/SUP], Jaisoorya Ts[SUP] 1 [/SUP], Janardhanan C Narayanaswamy[SUP] 5 [/SUP], Shyam Sundar Arumugham[SUP] 1 [/SUP], Yc Janardhan Reddy[SUP] 1 [/SUP]
Affiliations
- PMID: 38141264
- DOI: 10.1016/j.psychres.2023.115625
There is limited data on the long-term effect of the COVID-19 pandemic on obsessive-compulsive disorder (OCD). We report on the course of a cohort of individuals with OCD followed-up over a period of one year during the first wave of the COVID-19 pandemic in India. A cohort of 240 individuals registered at a specialty OCD clinic was regularly followed-up using standardized rating tools at three months, six months, and one year into the onset of the COVID-19 pandemic in India. These were compared with clinical ratings recorded in a comparable historical cohort of 207 individuals with OCD, followed up during a non-pandemic year. The pandemic and non-pandemic (historical control) cohorts did not differ in illness severity and rate of relapse. It was found that COVID-19-related anxiety declined over time. Among those patients who were treatment responders prior to the pandemic, COVID-19-related anxiety and non-adherence to medication predicted a relapse of symptoms. Contrary to our expectations, the rate of relapse and illness trajectory in the pandemic cohort did not differ from the non-pandemic cohort, suggesting that the pandemic did not impact our largely medication-adherent cohort. Adherence to treatment seemed to have a protective effect during the pandemic.
Keywords: COVID-19; Coronavirus; Course; OCD; Obsessive-compulsive disorder; Outcome; Pandemic.