tetano
Editor, Senior Moderator
Eur J Radiol. 2010 Oct 19. [Epub ahead of print]
Radiographic study of severe Influenza-A (H1N1) disease in children.
Zhao C, Gan Y, Sun J.
Department of Radiology, Shenzhen Children's Hospital, No. 7019, Yitian Road, Futian District, Shenzhen 518026, China.
Abstract
OBJECTIVE: To characterize the radiographic findings of pediatric patients with severe Influenza-A (H1N1) disease.
METHODS: A retrospective study of data from chest X-ray, CT and MRI exam of 29 pediatric patients treated in intensive care unit for severe Influenza-A (H1N1) disease.
RESULTS: Disease developed quickly at early stage. Here are four types of radiographic findings. The disease continued to progress for 2-3 days and X-ray showed that all 29 patients had increased solid lesions with the existence of interstitial lesions. Four days later, all lung lesions showed absorption to certain degree. Fifteen days later, X-ray and CT showed complete or significant absorption in 19 cases (85.5%); delayed recovery was identified in 8 cases (27.6%), pulmonary fibrosis was found in 3 cases (10.3%), and 3 patients (10.3%) died. But the latter identified more lesions. Cranial CT and MRI were performed for 8 patients who had neurological symptoms. Of them, 3 cases (10.3%) were abnormal, showed symmetrical long T1 and T2 signal shadow in bilateral thalamus and longer T1 and T2 signals in the between. 3 cases had autopsy completed.
CONCLUSION: The severe Influenza-A (H1N1) among children progression was generally rapid in the first 3 days. The overall radiographic findings are similar to acute respiratory distress syndrome (ARDS). A small portion of the patients occurred acute necrotizing encephalopathy and plastic bronchitis.
Copyright ? 2010 Elsevier Ireland Ltd. All rights reserved.
PMID: 20965678 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20965678
Radiographic study of severe Influenza-A (H1N1) disease in children.
Zhao C, Gan Y, Sun J.
Department of Radiology, Shenzhen Children's Hospital, No. 7019, Yitian Road, Futian District, Shenzhen 518026, China.
Abstract
OBJECTIVE: To characterize the radiographic findings of pediatric patients with severe Influenza-A (H1N1) disease.
METHODS: A retrospective study of data from chest X-ray, CT and MRI exam of 29 pediatric patients treated in intensive care unit for severe Influenza-A (H1N1) disease.
RESULTS: Disease developed quickly at early stage. Here are four types of radiographic findings. The disease continued to progress for 2-3 days and X-ray showed that all 29 patients had increased solid lesions with the existence of interstitial lesions. Four days later, all lung lesions showed absorption to certain degree. Fifteen days later, X-ray and CT showed complete or significant absorption in 19 cases (85.5%); delayed recovery was identified in 8 cases (27.6%), pulmonary fibrosis was found in 3 cases (10.3%), and 3 patients (10.3%) died. But the latter identified more lesions. Cranial CT and MRI were performed for 8 patients who had neurological symptoms. Of them, 3 cases (10.3%) were abnormal, showed symmetrical long T1 and T2 signal shadow in bilateral thalamus and longer T1 and T2 signals in the between. 3 cases had autopsy completed.
CONCLUSION: The severe Influenza-A (H1N1) among children progression was generally rapid in the first 3 days. The overall radiographic findings are similar to acute respiratory distress syndrome (ARDS). A small portion of the patients occurred acute necrotizing encephalopathy and plastic bronchitis.
Copyright ? 2010 Elsevier Ireland Ltd. All rights reserved.
PMID: 20965678 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20965678