tetano
Editor, Senior Moderator
Radiol Case Rep
. 2021 Jun 3.
doi: 10.1016/j.radcr.2021.05.072. Online ahead of print.
Acute Necrotic Hemorrhagic Leukoencephalitis related to COVID-19: a report of two cases
Alwaleed Alqahtani[SUP] 1 [/SUP], Aeed Alaklabi[SUP] 1 [/SUP], Stefan Kristjansson[SUP] 2 [/SUP], Hanan Alharthi[SUP] 2 [/SUP], Suhayb Aldhilan[SUP] 3 [/SUP], Hamid Alam[SUP] 4 [/SUP]
Affiliations
Abstract
Acute necrotic hemorrhagic leukoencephalitis (ANHLE) is a sub-form of acute disseminating leukoencephalitis which is a post viral or vaccination uncommon disease with poor prognosis. Radiological findings include multiple or diffuse lesions involving the white matter and sparing the cortex with or without rim enhancement. In addition to areas of hemorrhages with possible involvement of basal ganglia and thalami. We describe the imaging findings for two cases of ANHLE; a 59 years old male and a 47 years old female. Both of them were tested positive of SARS-Covid2 with presentation of consciousness loss and respiratory failure. CT and MRI brain show global white matter changes associated with acute hemorrhagic necrosis, although uncommon, are compatible with post-viral acute necrotic hemorrhagic leukoencephalitis with end point of death for the first patient and coma for the second patient.
Keywords: Abbreviation: SARS-COVID2, COVID-19; CT, Computed Tomography; DM, Diabetes Mellitus; DNR, Do Not Resuscitation; EEG, electroencephalogram; ESRD, End Stage Renal Disease; GCS, Glasgow Coma Score; HTN, Hypertension; ICU, Intensive Care Unit; MRI, Magnetic resonance imaging; SARS-COVID2. COVID-19. Coronavirus. Neuroimaging. Brain. White matter disease. Acute hemorrhagic necrosis; VAP, Ventilator associated Pneumonia.
. 2021 Jun 3.
doi: 10.1016/j.radcr.2021.05.072. Online ahead of print.
Acute Necrotic Hemorrhagic Leukoencephalitis related to COVID-19: a report of two cases
Alwaleed Alqahtani[SUP] 1 [/SUP], Aeed Alaklabi[SUP] 1 [/SUP], Stefan Kristjansson[SUP] 2 [/SUP], Hanan Alharthi[SUP] 2 [/SUP], Suhayb Aldhilan[SUP] 3 [/SUP], Hamid Alam[SUP] 4 [/SUP]
Affiliations
- PMID: 34104284
- PMCID: PMC8173541
- DOI: 10.1016/j.radcr.2021.05.072
Abstract
Acute necrotic hemorrhagic leukoencephalitis (ANHLE) is a sub-form of acute disseminating leukoencephalitis which is a post viral or vaccination uncommon disease with poor prognosis. Radiological findings include multiple or diffuse lesions involving the white matter and sparing the cortex with or without rim enhancement. In addition to areas of hemorrhages with possible involvement of basal ganglia and thalami. We describe the imaging findings for two cases of ANHLE; a 59 years old male and a 47 years old female. Both of them were tested positive of SARS-Covid2 with presentation of consciousness loss and respiratory failure. CT and MRI brain show global white matter changes associated with acute hemorrhagic necrosis, although uncommon, are compatible with post-viral acute necrotic hemorrhagic leukoencephalitis with end point of death for the first patient and coma for the second patient.
Keywords: Abbreviation: SARS-COVID2, COVID-19; CT, Computed Tomography; DM, Diabetes Mellitus; DNR, Do Not Resuscitation; EEG, electroencephalogram; ESRD, End Stage Renal Disease; GCS, Glasgow Coma Score; HTN, Hypertension; ICU, Intensive Care Unit; MRI, Magnetic resonance imaging; SARS-COVID2. COVID-19. Coronavirus. Neuroimaging. Brain. White matter disease. Acute hemorrhagic necrosis; VAP, Ventilator associated Pneumonia.