tetano
Editor, Senior Moderator
Interdiscip Sci. 2009 Dec;1(4):303-307. Epub 2009 Nov 14.
Rationale for cross-species infection and cross-subtype mutation in hemagglutinins from influenza A virus.
Yan SM, Wu G.
National Engineering Research Center for Non-food Biorefinery, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, P.R. China.
Abstract
The current H1N1 swine pandemic raises the question why the cross-species infection and cross-subtype mutation are so easy. In this study, we use ANOVA to analyze all influenza A virus hemagglutinins available in database in order to answer this question. The results show that there are differences between species and between subtypes in most cases, but the intra-subtype/species variation is generally larger than the inter-subtype/species variation, which provides the rational for cross-species infection and cross-subtype mutation.
PMID: 20640809 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20640809
Rationale for cross-species infection and cross-subtype mutation in hemagglutinins from influenza A virus.
Yan SM, Wu G.
National Engineering Research Center for Non-food Biorefinery, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, P.R. China.
Abstract
The current H1N1 swine pandemic raises the question why the cross-species infection and cross-subtype mutation are so easy. In this study, we use ANOVA to analyze all influenza A virus hemagglutinins available in database in order to answer this question. The results show that there are differences between species and between subtypes in most cases, but the intra-subtype/species variation is generally larger than the inter-subtype/species variation, which provides the rational for cross-species infection and cross-subtype mutation.
PMID: 20640809 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20640809