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Recovery of Pulmonary functions, Exercise Capacity and Quality of Life after Pulmonary Rehabilitation in Survivors of ARDS due to Severe Influenza A (

tetano

Editor, Senior Moderator
Influenza Other Respir Viruses. 2018 Apr 20. doi: 10.1111/irv.12566. [Epub ahead of print]
[h=1]Recovery of Pulmonary functions, Exercise Capacity and Quality of Life after Pulmonary Rehabilitation in Survivors of ARDS due to Severe Influenza A (H1N1) Pneumonitis.[/h] Hsieh MJ[SUP]1,[/SUP][SUP]2[/SUP], Lee WJ[SUP]1[/SUP], Cho HY[SUP]3[/SUP], Wu MF[SUP]3[/SUP], Hu HC[SUP]2,[/SUP][SUP]4,[/SUP][SUP]3[/SUP], Kao KC[SUP]2,[/SUP][SUP]4,[/SUP][SUP]3[/SUP], Chen NH[SUP]2,[/SUP][SUP]4,[/SUP][SUP]3[/SUP], Tsai YH[SUP]1,[/SUP][SUP]2[/SUP], Huang CC[SUP]2,[/SUP][SUP]4,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Acute respiratory distress syndrome (ARDS) due to severe influenza A H1N1 pneumonitis would result in impaired pulmonary functions and health-related quality of life (HRQoL) after hospital discharge.
[h=4]OBJECTIVES:[/h] The recovery of pulmonary functions, exercise capacity and HRQoL in the survivors of ARDS due to 2009 pandemic influenza A H1N1 pneumonitis (H1N1-ARDS) were evaluated in a tertiary teaching hospital in the northern Taiwan between May 2010 and June 2011.
[h=4]PATIENTS AND METHODS:[/h] Data of spirometry, total lung capacity (TLC), diffusing capacity of carbon monoxide (DL[SUB]CO[/SUB] ), 6-minute walk distance (6MWD) in the patients survived from H1N1-ARDS were collected 1, 3 and 6 months post hospital discharge. HRQoL was evaluated with St. George respiratory questionnaire (SGRQ).
[h=4]RESULTS:[/h] Nine survivors of H1N1-ARDS in the study period were included. All these patients received two months' pulmonary rehabilitation program. Pulmonary functions and exercise capacity included TLC, forced vital capacity (FVC), forced expiratory volume in the first second (FEV[SUB]1[/SUB] ), DL[SUB]CO[/SUB] and 6MWD improved from 1 to 3 months post hospital discharge. Only TLC had further significant improvement from 3 to 6 months. HRQoL represented as the total score of SGRQ had no significant improvement in the first 3 months but improved significantly from 3 to 6 months post discharge.
[h=4]CONCLUSION:[/h] The impaired pulmonary functions and exercise capacity in the survivors of H1N1-ARDS improved soon at 3 months after hospital discharge. Their quality of life had keeping improved at 6 months even though there was no further improvement of their pulmonary functions and exercise capacity. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.


[h=4]KEYWORDS:[/h] Acute respiratory distress syndrome; Exercise capacity; Influenza A H1N1; Pulmonary function tests; Quality of life

PMID: 29676537 DOI: 10.1111/irv.12566
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