Respir Investig . The real-time reverse transcription-polymerase chain reaction threshold cycle values for severe acute respiratory syndrome coronav

[tetano]

Respir Investig


. 2021 Jan 28;S2212-5345(21)00008-3.
doi: 10.1016/j.resinv.2020.12.011. Online ahead of print.
The real-time reverse transcription-polymerase chain reaction threshold cycle values for severe acute respiratory syndrome coronavirus 2 predict the prognosis of coronavirus disease 2019 pneumonia


Takahiro Fukushima[SUP] 1 [/SUP], Hiroki Kabata[SUP] 2 [/SUP], Ryo Yamamoto[SUP] 1 [/SUP], Tomohiro Suhara[SUP] 1 [/SUP], Yoshifumi Uwamino[SUP] 1 [/SUP], Yasushi Kondo[SUP] 1 [/SUP], Katsunori Masaki[SUP] 1 [/SUP], Hirofumi Kamata[SUP] 1 [/SUP], Hiromasa Nagata[SUP] 1 [/SUP], Koichiro Homma[SUP] 1 [/SUP], Yuko Kaneko[SUP] 1 [/SUP], Makoto Ishii[SUP] 1 [/SUP], Junichi Sasaki[SUP] 1 [/SUP], Hiroshi Morisaki[SUP] 1 [/SUP], Naoki Hasegawa[SUP] 1 [/SUP], Koichi Fukunaga[SUP] 1 [/SUP], Keio Donner Project Team



Affiliations

• PMID: 33582075
• DOI: 10.1016/j.resinv.2020.12.011

Abstract

The clinical course of coronavirus disease 2019 (COVID-19) varies from mild to critical. We retrospectively examined whether clinical and laboratory findings on admission could predict COVID-19 prognosis. Among various factors associated with COVID-19 severity, our results indicated that the real-time reverse transcription-polymerase chain reaction (RT-PCR) threshold cycle (Ct) values for severe acute respiratory syndrome coronavirus 2 were the most useful predictor of COVID-19 prognosis.

Keywords: COVID-19; Prognosis; SARS-CoV-2; Severity.