tetano
Editor, Senior Moderator
Respiration
. 2021 Mar 30;1-5.
doi: 10.1159/000514928. Online ahead of print.
Pre-Procedural COVID-19 Nasopharyngeal Swab Has Good Concordance with Bronchoalveolar Lavage in Patients at Low Risk for Viral Infection
Catherine L Oberg[SUP] 1 [/SUP], Reza Ronaghi[SUP] 1 [/SUP], Erik E Folch[SUP] 2 [/SUP], Colleen L Channick[SUP] 1 [/SUP], Tao He[SUP] 1 [/SUP], Irawan Susanto[SUP] 1 [/SUP], Scott S Oh[SUP] 1 [/SUP]
Affiliations
Abstract
Background: The coronavirus disease 2019 (COVID-19) pandemic has drastically affected hospital and operating room (OR) workflow around the world as well as trainee education. Many institutions have instituted mandatory preoperative SARS-CoV-2 PCR nasopharyngeal swab (NS) testing in patients who are low risk for COVID-19 prior to elective cases. This method, however, is challenging as the sensitivity, specificity, and overall reliability of testing remains unclear.
Objectives: The objective of this study was to assess the concordance of a negative NS in low risk preoperative patients with lower airway bronchoalveolar lavage (BAL) specimens obtained from the same patients.
Methods: We prospectively sent intraoperative lower airway BAL samples collected within 48 h of a negative mandatory preoperative NS for SARS-CoV-2 PCR testing. All adult patients undergoing a scheduled bronchoscopic procedure for any reason were enrolled, including elective and nonelective cases.
Results: One-hundred eighty-nine patients were included. All BAL specimens were negative for SARS-CoV-2 indicative of 100% concordance between testing modalities.
Conclusions: These results are promising and suggest that preoperative nasopharyngeal SARS-CoV-2 testing provides adequate screening to rule out active COVID-19 infection prior to OR cases in a population characterized as low risk by negative symptom screening. This information can be used for both pre-procedural screening and when reintroducing trainees into the workforce.
Keywords: Bronchoscopy; Coronavirus disease 2019; Preoperative; SARS-CoV-2; Screening.
. 2021 Mar 30;1-5.
doi: 10.1159/000514928. Online ahead of print.
Pre-Procedural COVID-19 Nasopharyngeal Swab Has Good Concordance with Bronchoalveolar Lavage in Patients at Low Risk for Viral Infection
Catherine L Oberg[SUP] 1 [/SUP], Reza Ronaghi[SUP] 1 [/SUP], Erik E Folch[SUP] 2 [/SUP], Colleen L Channick[SUP] 1 [/SUP], Tao He[SUP] 1 [/SUP], Irawan Susanto[SUP] 1 [/SUP], Scott S Oh[SUP] 1 [/SUP]
Affiliations
- PMID: 33784700
- DOI: 10.1159/000514928
Abstract
Background: The coronavirus disease 2019 (COVID-19) pandemic has drastically affected hospital and operating room (OR) workflow around the world as well as trainee education. Many institutions have instituted mandatory preoperative SARS-CoV-2 PCR nasopharyngeal swab (NS) testing in patients who are low risk for COVID-19 prior to elective cases. This method, however, is challenging as the sensitivity, specificity, and overall reliability of testing remains unclear.
Objectives: The objective of this study was to assess the concordance of a negative NS in low risk preoperative patients with lower airway bronchoalveolar lavage (BAL) specimens obtained from the same patients.
Methods: We prospectively sent intraoperative lower airway BAL samples collected within 48 h of a negative mandatory preoperative NS for SARS-CoV-2 PCR testing. All adult patients undergoing a scheduled bronchoscopic procedure for any reason were enrolled, including elective and nonelective cases.
Results: One-hundred eighty-nine patients were included. All BAL specimens were negative for SARS-CoV-2 indicative of 100% concordance between testing modalities.
Conclusions: These results are promising and suggest that preoperative nasopharyngeal SARS-CoV-2 testing provides adequate screening to rule out active COVID-19 infection prior to OR cases in a population characterized as low risk by negative symptom screening. This information can be used for both pre-procedural screening and when reintroducing trainees into the workforce.
Keywords: Bronchoscopy; Coronavirus disease 2019; Preoperative; SARS-CoV-2; Screening.